SynthesisTechniques in coloproctology2014
Mucinous carcinoma of the rectum: a distinct clinicopathological entity.
Synthesis in Techniques in coloproctology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- The impact of neoadjuvant chemotherapy on safety and long-term survival in patients with locally advanced colon cancer.World journal of surgical oncology · 2026Article
- Nomogram based on MRI images and clinical data for differentiating mucinous from non-mucinous rectal adenocarcinoma.BMC medical imaging · 2025Article
- Imaging of young-onset colorectal cancer: what the radiologist needs to know.Abdominal radiology (New York) · 2025Review
- Mucinous adenocarcinoma of the rectum masquerading as inflammatory bowel disease-a case report.Journal of surgical case reports · 2025Article
- Surgical management of mucinous adenocarcinoma arising in perianal fistula: A case series.Surgery open science · 2025Article
- Propensity-score matched outcomes of minimally invasive and open pelvic exenteration in locally advanced rectal cancer.Updates in surgery · 2025Article
- Local Recurrence of Premalignant and Early Malignant Rectal Polyps Treated by TEM-A Single-Center Experience.Journal of clinical medicine · 2024Article
- Does stage III rectal mucinous adenocarcinoma benefit from neoadjuvant chemoradiation?Techniques in coloproctology · 2024Article
- The Role of Predictive and Prognostic MRI-Based Biomarkers in the Era of Total Neoadjuvant Treatment in Rectal Cancer.Cancers · 2024Review
- Waist subcutaneous soft tissue metastasis of rectal mucinous adenocarcinoma: A case report.World journal of clinical cases · 2024Article
- Risk stratification of stage II rectal mucinous adenocarcinoma to predict the benefit of adjuvant chemotherapy following neoadjuvant chemoradiation and surgery.Frontiers in oncology · 2024Article
- Quantitative synthetic MRI for predicting locally advanced rectal cancer response to neoadjuvant chemoradiotherapy.European radiology · 2023Article
- Mucinous adenocarcinoma: A unique clinicopathological subtype in colorectal cancer.World journal of gastrointestinal surgery · 2021Review
- Unusual Presentation of Carcinoma Rectum-a Case Report.Indian journal of surgical oncology · 2021Article
- Current controversy, confusion, and imprecision in the use and interpretation of rectal MRI.Abdominal radiology (New York) · 2019Review
- Mucinous adenocarcinoma arising from chronic perianal fistula-a multidisciplinary approach.Journal of gastrointestinal oncology · 2019Article
- Mucinous colorectal adenocarcinoma: clinical pathology and treatment options.Cancer communications (London, England) · 2019Review
- Response evaluation after neoadjuvant treatment for rectal cancer using modern MR imaging: a pictorial review.Insights into imaging · 2019Review
- Application of magnetic resonance diffusion kurtosis imaging for distinguishing histopathologic subtypes and grades of rectal carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019Article
- Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.Clinical colorectal cancer · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe definition of mucinous tumours relies on quantification of the amount of mucus produced by neoplastic cells within the rectum. This has changed over the years to include varying degrees of mucin production. The inconsistency of diagnosis has led to conflicting reports in the literature regarding clinical outcomes and treatment response. A universally accepted definition and improved imaging and surgical techniques in the last decade are now challenging the traditional view of these tumours. The aim of this review was to present the current evidence on the clinicopathological characteristics of mucinous tumours of the rectum.
methodsA systematic review was conducted using Preferred Reporting for Systematic Reviews and Meta-Analyses guidelines. A literature search was performed using the Ovid SP to search both EMBASE and MEDLINE databases, Google Scholar and PubMed to find all studies relating to mucinous carcinoma of the rectum. The search dates were between 1 January 1965 and 1 March 2013.
resultsMucinous tumours comprise 5-20 % of all rectal cancers and commonly present at a more advanced stage and in younger patients. They are readily identified on MRI, and the diagnosis is confirmed on histological analysis, demonstrating more than 50 % of extracellular mucin within the tumour complex. They carry an overall worse prognosis compared to adenocarcinoma of the same stage. The response to oncological treatment remains controversial.
conclusionMucinous tumours of the rectum are less well understood than non-mucinous adenocarcinoma. This is due to the inconsistent histopathological definitions of the past making comparison of clinical outcome data difficult. They remain challenging to treat and are associated with a poor prognosis. A universally accepted definition and the role of imaging techniques such as MRI to accurately detect mucinous tumours are likely to lead to a better understanding of these cancers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.