Observational studyCritical care (London, England)2013
Diagnosis and management of temperature abnormality in ICUs: a EUROBACT investigators' survey.
Observational study in Critical care (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Antipyretic Therapy in Critically Ill Septic Patients: A Systematic Review and Meta-Analysis.Critical care medicine · 2017Pooled it
- Respective impact of lowering body temperature and heart rate on mortality in septic shock: mediation analysis of a randomized trial.Intensive care medicine · 2015Trial
- The poikilothermic hypothesis of sepsis.Critical care (London, England) · 2026Review
- Prognostic usefulness of temperature in congestive heart failure with acute myocardial infarction: a retrospective cohort study.European journal of medical research · 2026Article
- Sepsis in the absence of fever: Determining the criteria for and feasibility of future therapeutic temperature management trials.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025Article
- Fever in Sepsis Revisited: Is a Little Heat What We Need?Open forum infectious diseases · 2025Review
- Source control in bloodstream infections in patients with sepsis, septic shock, or requiring ICU admission: a scoping review with recommendations for standardizing research.Intensive care medicine · 2025Article
- Construction and evaluation of shortZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- Ten tips on fever.Intensive care medicine · 2023Article
- Review
- Temperature control in sepsis.Frontiers in medicine · 2023Review
- Fever and Antipyretic Supported by Traditional Chinese Medicine: A Multi-Pathway Regulation.Frontiers in pharmacology · 2021Review
- Article
- The Association of Fever and Antipyretic Medication With Outcomes in Mechanically Ventilated Patients: A Cohort Study.Shock (Augusta, Ga.) · 2019Article
- Should we treat pyrexia? And how do we do it?Critical care (London, England) · 2016Review
- Controversies in the temperature management of critically ill patients.Journal of anesthesia · 2016Review
- Pyrexia: aetiology in the ICU.Critical care (London, England) · 2016Review
- [Is control fever mandatory in severe infections?]Reanimation : journal de la Societe de reanimation de langue francaise · 2016Article
- Management of Intra-abdominal Infections due to Carbapenemase-Producing Organisms.Current infectious disease reports · 2014Article
- Management of severe infections: A time to keep a cool head or a hot topic for clinical trials?The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough fever and hypothermia are common abnormal physical signs observed in patients admitted to intensive care units (ICU), little data exist on their optimal management. The objective of this study was to describe contemporary practices and determinants of management of temperature abnormalities among patients admitted to ICUs.
methodsSite leaders of the multi-national EUROBACT study were surveyed regarding diagnosis and management of temperature abnormalities among patients admitted to their ICUs.
resultsOf the 162 ICUs originally included in EUROBACT, responses were received from 139 (86%) centers in 23 countries in Europe (117), South America (8), Asia (5), North America (4), Australia (3) and Africa (2). A total of 117 (84%) respondents reported use of a specific temperature threshold in their ICU to define fever. A total of 14 different discrete levels were reported with a median of 38.2°C (inter-quartile range, IQR, 38.0°C to 38.5°C). The use of thermometers was protocolized in 91 (65%) ICUs and a wide range of methods were reportedly used, with axillary, tympanic and urinary bladder sites as the most common as primary modalities. Only 31 (22%) of respondents indicated that there was a formal written protocol for temperature control among febrile patients in their ICUs. In most or all cases practice was to control temperature, to use acetaminophen, and to perform a full septic workup in febrile patients and that this was usually directed by physician order. While reported practice was to treat nearly all patients with neurological impairment and most patients with acute coronary syndromes and infections, severe sepsis and septic shock, this was not the case for most patients with liver failure and fever.
conclusionsA wide range of definitions and management practices were reported regarding temperature abnormalities in the critically ill. Documenting temperature abnormality management practices, including variability in clinical care, is important to inform planning of future studies designed to optimize infection and temperature management strategies in the critically ill.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.