ReviewBriefings in functional genomics2014
C. elegans epigenetic regulation in development and aging.
Review in Briefings in functional genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Epigenetics and individuality: from concepts to causality across timescales.Nature reviews. Genetics · 2025Review
- Chromatin and epigenetics in aging biology.Genetics · 2025Review
- Anti-Obesity Properties of a Novel Probiotic Strain ofInternational journal of molecular sciences · 2025Article
- Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin.Science advances · 2024Article
- CUT&RUN for Chromatin Profiling in Caenorhabditis elegans.Current protocols · 2022Article
- Review
- Epigenetic effects induced by silver nanoparticles in Caenorhabditis elegans after multigenerational exposure.The Science of the total environment · 2020Article
- AMPK Regulates Developmental Plasticity through an Endogenous Small RNA Pathway inInternational journal of molecular sciences · 2020Review
- Emerging Roles for Chromo Domain Proteins in Genome Organization and Cell Fate inFrontiers in cell and developmental biology · 2020Review
- Behavioral Mechanisms That Depend on Dopamine and Serotonin inJournal of experimental neuroscience · 2018Article
- Recent advances in understanding/assessing toxicity to the epigenome.F1000Research · 2017Review
- Analysis of C. elegans muscle transcriptome using trans-splicing-based RNA tagging (SRT).Nucleic acids research · 2016Article
- Article
- Lack of pairing during meiosis triggers multigenerational transgene silencing in Caenorhabditis elegans.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans.Genome biology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The precise developmental map of the Caenorhabditis elegans cell lineage, as well as a complete genome sequence and feasibility of genetic manipulation make this nematode species highly attractive to study the role of epigenetics during development. Genetic dissection of phenotypical traits, such as formation of egg-laying organs or starvation-resistant dauer larvae, has illustrated how chromatin modifiers may regulate specific cell-fate decisions and behavioral programs. Moreover, the transparent body of C. elegans facilitates non-invasive microscopy to study tissue-specific accumulation of heterochromatin at the nuclear periphery. We also review here recent findings on how small RNA molecules contribute to epigenetic control of gene expression that can be propagated for several generations and eventually determine longevity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.