ArticleParasites & vectors2013
Co-infection of Borrelia burgdorferi sensu lato and Rickettsia species in ticks and in an erythema migrans patient.
Article in Parasites & vectors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 55 citations in OpenAlex.
- Tick-Borne Infections: Results from a Prospective Observational Study from a Single Centre in Northern Italy.Pathogens (Basel, Switzerland) · 2026Observational
- Development and Evaluation of a Dual-Target One-Step Nested PCR for the Detection of Spotted Fever GroupPathogens (Basel, Switzerland) · 2026Article
- Tick-Borne Co-Infection in Lyme Disease: Clinical Impact, Diagnostic Challenges, and Therapeutic Perspectives.Microorganisms · 2026Review
- Review
- Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024Review
- Global prevalence ofBMJ open · 2024Article
- Ixodid ticks and zoonotic tick-borne pathogens of the Western Balkans.Parasites & vectors · 2024Review
- Exploring the Coinfection and Genetic Diversity of Multiple Tick-Borne Pathogens in Livestock Population of Punjab, Pakistan.Transboundary and emerging diseases · 2024Article
- Meta-analysis of tick-borne and other pathogens: Co-infection or co-detection? That is the question.Current research in parasitology & vector-borne diseases · 2024Review
- History and Current Status of Mediterranean Spotted Fever (MSF) in the Crimean Peninsula and Neighboring Regions along the Black Sea Coast.Pathogens (Basel, Switzerland) · 2023Review
- Lyme borreliosis diagnosis: state of the art of improvements and innovations.BMC microbiology · 2023Review
- Spotted fever group rickettsiae andNew microbes and new infections · 2023Article
- The Biological and Ecological Features of Northbound Migratory Birds, Ticks, and Tick-Borne Microorganisms in the African-Western Palearctic.Microorganisms · 2023Review
- Rare Case of Rickettsiosis Caused by Rickettsia monacensis, Portugal, 2021.Emerging infectious diseases · 2022Article
- Human Co-Infections betweenPathogens (Basel, Switzerland) · 2022Review
- Tick-transmitted co-infections among erythema migrans patients in a general practice setting in Norway: a clinical and laboratory follow-up study.BMC infectious diseases · 2021Article
- Temporal patterns in Ixodes ricinus microbial communities: an insight into tick-borne microbe interactions.Microbiome · 2021Article
- Ticking on Pandora's box: a prospective case-control study into 'other' tick-borne diseases.BMC infectious diseases · 2021Article
- Evaluation of Disease Causality of RarePathogens (Basel, Switzerland) · 2020Review
- A three-years assessment of Ixodes ricinus-borne pathogens in a French peri-urban forest.Parasites & vectors · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLyme borreliosis is the most prevalent tick-borne disease in Europe. Ixodes ricinus also carries other pathogenic bacteria, but corresponding human diseases are rarely reported. Here, we compared the exposure to Rickettsia helvetica and Rickettsia monacensis with that to Lyme borreliosis spirochetes. We assumed that their exposure corresponds to their infection rate in questing I. ricinus.
findingsThree Rickettsia species were detected in ticks with a total prevalence of 7.9%, of which the majority was R. helvetica (78%) and R. monacensis (21%). From the same geographic area, skin biopsies of erythema migrans patients were investigated for possible co-infections with Rickettsia spp.. Forty-seven out of 67 skin biopsies were PCR positive for Borrelia burgdorferi s.l. and one sample was positive for R. monacensis. The Borrelia genospecies from the R. monacensis positive patient was identified as Borrelia afzelii. The patient did not show any symptoms associated with rickettsiosis.
conclusionsCo-infections of I. ricinus with Rickettsia spp. and B. burgdorferi s.l. were as high as expected from the individual prevalence of both pathogens. Co-infection rate in erythema migrans patients corresponded well with tick infection rates. To our knowledge, this is the first reported co-infection of B. afzelii and R. monacensis.
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