Evidence map›Paper›PMID 24325897›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2014

Are glycans the Holy Grail for biomarkers of aging?

David G Le Couteur, Stephen J Simpson, Rafael de Cabo

Abstract readEditorialComment
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In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Heritability of the glycan clock of biological age.Frontiers in cell and developmental biology · 2022
    Article
  7. Common methods of biological age estimation.Clinical interventions in aging · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

David G Le CouteurCentre for Education and Research on Ageing and ANZAC Research Institute, University of Sydney and Concord Repatriation General Hospital, New South Wales, Australia. The Charles Perkins Centre and david.lecouteur@sydney.edu.au.
Stephen J SimpsonThe Charles Perkins Centre and School of Biological Sciences, University of Sydney, Australia.
Rafael de CaboTranslational Gerontology Branch, National Institute on Ageing, Baltimore.

Funding

Aging Intervention ProgramZIAAG000363 · NIA · NATIONAL INSTITUTE ON AGING · PI DE CABO, RAFAEL · 2009 to 2025
$9.0M
Calorie restriction and agingZIAAG000368 · NIA · NATIONAL INSTITUTE ON AGING · PI DE CABO, RAFAEL · 2009 to 2025
$6.9M
6 · The paper itself

Abstract

Posttranslational modifications of circulating proteins such as immunoglobulins may prove to be important biomarkers of aging.

Indexed as

AgingFemaleHumansImmunoglobulin GMalePolysaccharidesImmunoglobulin GPolysaccharidesBiomarkers of agingGlycans.

Identifiers

PMID24325897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.