ArticleJournal of the American Chemical Society2013
Meta-selective C-H functionalization using a nitrile-based directing group and cleavable Si-tether.
Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 251 citations in OpenAlex.
- A unified strategy for remote C-H fluorination of phenylacetic acids and their homologues at theChemical science · 2026Article
- Diversity-Oriented C-H Activation Reactions of the Naphthalene Scaffold.Journal of the American Chemical Society · 2025Article
- Ruthenium-catalyzed three-component tandem remote C-H functionalization of naphthalenes: modular and concise synthesis of multifunctional naphthalenes.Chemical science · 2025Article
- Benzoyldiisopropylchlorosilane: a visible light photocleavable alcohol protecting group.Chemical science · 2023Article
- MacrocyclizationChemical science · 2023Article
- Transition-Metal-Catalyzed C-H Bond Activation for the Formation of C-C Bonds in Complex Molecules.Chemical reviews · 2023Review
- DistalChemical science · 2023Article
- Pd(ii)-catalyzedChemical science · 2022Article
- RhodiumChemical science · 2022Article
- Directing group assisted rhodium catalyzedChemical science · 2022Article
- Empirical Guidelines for the Development of Remote Directing Templates through Quantitative and Experimental Analyses.Journal of the American Chemical Society · 2022Article
- The Activating Effect of Strong Acid for Pd-Catalyzed Directed C-H Activation by Concerted Metalation-Deprotonation Mechanism.Molecules (Basel, Switzerland) · 2021Article
- Hexafluoroisopropanol: the magical solvent for Pd-catalyzed C-H activation.Chemical science · 2021Review
- Recent development in transition metal-catalysed C-H olefination.Chemical science · 2021Review
- Achieving Site-Selectivity for C-H Activation Processes Based on Distance and Geometry: A Carpenter's Approach.Journal of the American Chemical Society · 2020Review
- Silanol: a bifunctional group for peptide synthesis and late-stage functionalization.Chemical science · 2020Article
- Article
- Rational Development of Remote C-H Functionalization of Biphenyl: Experimental and Computational Studies.Angewandte Chemie (International ed. in English) · 2020Article
- Article
- Development of an Imine Chaperone for Selective C-H Functionalization of Alcohols via Radical Relay.The Journal of organic chemistry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A nitrile-based template that enables meta-selective C-H bond functionalization was developed. The template is applicable to a range of substituted arenes and tolerates a variety of functional groups. The directing group uses a silicon atom for attachment, allowing for a facile introduction/deprotection strategy increasing the synthetic practicality of this template.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.