Evidence map›Paper›PMID 24324979›Full record

ArticleJournal of immunological techniques in infectious diseases2013

A Viable and Simple Self-Sampling Method for Human Papillomavirus Detection among South African Adolescents.

David H Adler, Fatima Laher, Erica Lazarus, Katherine Grzesik, Glenda E Gray, Bruce Allan, Anna-Lise Williamson

Abstract read
In one paragraph

Article in Journal of immunological techniques in infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David H AdlerDepartment of Emergency Medicine, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Fatima Laher
Erica Lazarus
Katherine Grzesik
Glenda E Gray
Bruce Allan
Anna-Lise Williamson

Funding

Virology/Immunology CoreP30AI078498 · NIAID · UNIVERSITY OF ROCHESTER · PI DEWHURST, STEPHEN · 2008 to 2018
$14.6M
Post-Vacc. HPV Genotype Distr. Among HIV+ and HIV- Young Women in S. AfricaK23AI077759 · NIAID · UNIVERSITY OF ROCHESTER · PI ADLER, DAVID H · 2010 to 2014
$627k
NIAID NIH HHS K23 AI077759NIAID NIH HHS P30 AI078498
6 · The paper itself

Abstract

backgroundSelf-sampling for Human Papillomavirus (HPV) testing may offer improved patient acceptability, decreased cost, and greater practicality than clinician collection of specimens. HPV testing among adolescents is necessary to conduct vaccine surveillance and may play a role in cervical cancer screening among some populations.

methodsA cross-sectional prevalence study was conducted to compare the results of self-collected and clinician-collected specimens for Human papillomavirus (HPV) testing among South African adolescent females. All participants provided self-sampled vaginal swabs and underwent clinician-collection of cervical swabs for HPV DNA analysis. The level of agreement between HPV DNA results from the two specimen collection methods was measured.

resultsThe level of agreement between HPV DNA results from self-collected and clinician-collected specimens was high (κ=86.7; p<0.001). A high prevalence of HPV overall was found by both specimen collection methods (57%; 95% CI 0.37-0.75). Low-risk HPV (LR-HPV) types were found slightly more frequently in self-collected specimens.

conclusionThere is a high level of agreement between the HPV DNA results from self-collected and clinician-collected specimens. Self-collection of specimens for HPV testing is a viable alternative among adolescents.

Indexed as

AdolescentCervical cancer preventionHuman papillomavirusSelf-samplingSouth Africa

Identifiers

PMID24324979
PMCPMC3855317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.