Evidence map›Paper›PMID 24324605›Full record

ArticlePloS one2013

Association between infancy BMI peak and body composition and blood pressure at age 5-6 years.

Michel H P Hof, Tanja G M Vrijkotte, Marieke L A de Hoog, Manon van Eijsden, Aeilko H Zwinderman

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Michel H P HofDepartment of Clinical Epidemiology, Bioinformatics, and Biostatistics, Academic Medical Center-University of Amsterdam, Amsterdam, The Netherlands ; Department of Public Health, Academic Medical Center-University of Amsterdam, Amsterdam, The Netherlands.
Tanja G M Vrijkotte
Marieke L A de Hoog
Manon van Eijsden
Aeilko H Zwinderman
University of Amsterdam · NLAcademic Medical Center · NLGGD Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe development of overweight is often measured with the body mass index (BMI). During childhood the BMI curve has two characteristic points: the adiposity rebound at 6 years and the BMI peak at 9 months of age. In this study, the associations between the BMI peak and body composition measures and blood pressure at age 5-6 years were investigated.

methodsMeasurements from the Amsterdam Born Children and their Development (ABCD) study were available for this study. Blood pressure (systolic and diastolic) and body composition measures (BMI, waist-to-height ratio, fat percentage) were gathered during a health check at about 6 years of age (n = 2822). All children had multiple BMI measurements between the 0-4 years of age. For boys and girls separately, child-specific BMI peaks were extracted from mixed effect models. Associations between the estimated BMI peak and the health check measurements were analysed with linear models. In addition, we investigated the potential use of the BMI at 9 months as a surrogate measure for the magnitude of the BMI peak.

resultsAfter correction for the confounding effect of fetal growth, both timing and magnitude of the BMI peak were significantly and positively associated (p<0.001) with all body composition measures at the age of 5-6 years. The BMI peak showed no direct association with blood pressure at the age 5-6 year, but was mediated by the current BMI. The correlation between the magnitude of the BMI peak and BMI at 9 months was approximately 0.93 and similar associations with the measures at 5-6 years were found.

conclusionThe magnitude of the BMI peak was associated with body composition measures at 5-6 years of age. Moreover, the BMI at 9 months could be used as surrogate measure for the magnitude of the BMI peak.

Indexed as

Body CompositionBody Mass IndexBlood PressureChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornLinear ModelsMaleNetherlandsRisk Factors

Identifiers

PMID24324605
PMCPMC3851737
OpenAlexW1970008163

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.