ArticlePloS one2013
Asynchronicity of facial blood perfusion in migraine.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Exploring Facial Thermography Patterns in Women with Chronic Migraine.Journal of clinical medicine · 2023Article
- Facial functional networks during resting state revealed by thermal infrared imaging.Physical and engineering sciences in medicine · 2023Article
- Left- vs right-sided migraine: a scoping review.Journal of neurology · 2023Article
- On the spatial phase distribution of cutaneous low-frequency perfusion oscillations.Scientific reports · 2022Article
- Photoplethysmographic Imaging of Hemodynamics and Two-Dimensional Oximetry.Optics and spectroscopy · 2022Article
- Changes in Cerebral Blood Flow after Erenumab Treatment in Good and Non-Responders-A Pilot Study of Migraine Patients.Journal of clinical medicine · 2021Article
- An iPPG-Based Device for Pervasive Monitoring of Multi-Dimensional Cardiovascular Hemodynamics.Sensors (Basel, Switzerland) · 2021Article
- Phase Velocity of Facial Blood Volume Oscillation at a Frequency of 0.1 Hz.Frontiers in physiology · 2021Article
- Vitamin C Acutely Affects Brain Perfusion and Mastication-Induced Perfusion Asymmetry in the Principal Trigeminal Nucleus.Frontiers in systems neuroscience · 2021Article
- Migrainous facial palsy (MFP): the introduction of a new concept of neurovascular conflict and its preliminary clinical evidence.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Low-frequency facial hemodynamic oscillations distinguish migraineurs from non-headache controls.Cephalalgia reports · 2019Article
- Novel capsaicin-induced parameters of microcirculation in migraine patients revealed by imaging photoplethysmography.The journal of headache and pain · 2018Article
- The value of polarization in camera-based photoplethysmography.Biomedical optics express · 2017Article
- Parasympathetic Cholinergic and Neuropeptide Mechanisms of Migraine.Anesthesiology and pain medicine · 2017Review
- Accurate measurement of the pulse wave delay with imaging photoplethysmography.Biomedical optics express · 2016Article
- Skin inhomogeneity as a source of error in remote PPG-imaging.Biomedical optics express · 2016Article
- Motion robust PPG-imaging through color channel mapping.Biomedical optics express · 2016Article
- Autonomous control of cardiovascular reactivity in patients with episodic and chronic forms of migraine.The journal of headache and pain · 2016Article
- Article
- Ambiguity of mapping the relative phase of blood pulsations.Biomedical optics express · 2014Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asymmetrical changes in blood perfusion and asynchronous blood supply to head tissues likely contribute to migraine pathophysiology. Imaging was widely used in order to understand hemodynamic variations in migraine. However, mapping of blood pulsations in the face of migraineurs has not been performed so far. We used the Blood Pulsation Imaging (BPI) technique, which was recently developed in our group, to establish whether 2D-imaging of blood pulsations parameters can reveal new biomarkers of migraine. BPI characteristics were measured in migraineurs during the attack-free interval and compared to healthy subjects with and without a family history of migraine. We found a novel phenomenon of transverse waves of facial blood perfusion in migraineurs in contrast to healthy subjects who showed synchronous blood delivery to both sides of the face. Moreover, the amplitude of blood pulsations was symmetrically distributed over the face of healthy subjects, but asymmetrically in migraineurs and subjects with a family history of migraine. In the migraine patients we found a remarkable correlation between the side of unilateral headache and the direction of the blood perfusion wave. Our data suggest that migraine is associated with lateralization of blood perfusion and asynchronous blood pulsations in the facial area, which could be due to essential dysfunction of the autonomic vascular control in the face. These findings may further enhance our understanding of migraine pathophysiology and suggest new easily available biomarkers of this pathology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.