ReviewClinical & developmental immunology2013
Influence of the cholinergic system on the immune response of teleost fishes: potential model in biomedical research.
Review in Clinical & developmental immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 32 citations in OpenAlex.
- Modulation of the intestinal mucosal and cell-mediated response against natural helminth infection in the African catfish Clarias gariepinus.BMC veterinary research · 2024Article
- Coupling of Sharp Wave Events between Zebrafish Hippocampal and Amygdala Homologs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Organophosphorus Pesticides as Modulating Substances of Inflammation through the Cholinergic Pathway.International journal of molecular sciences · 2022Review
- Transcriptomic Analysis of Fish Hosts Responses to Nervous Necrosis Virus.Pathogens (Basel, Switzerland) · 2022Review
- A Critical Review of Zebrafish Models of Parkinson's Disease.Frontiers in pharmacology · 2022Review
- Behavioural Fever Promotes an Inflammatory Reflex Circuit in Ectotherms.International journal of molecular sciences · 2021Article
- Modulation of immune response by organophosphorus pesticides: fishes as a potential model in immunotoxicology.Journal of immunology research · 2015Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fishes are the phylogenetically oldest vertebrate group, which includes more than one-half of the vertebrates on the planet; additionally, many species have ecological and economic importance. Fish are the first evolved group of organisms with adaptive immune mechanisms; consequently, they are an important link in the evolution of the immune system, thus a potential model for understanding the mechanisms of immunoregulation. Currently, the influence of the neurotransmitter acetylcholine (ACh) on the cells of the immune system is widely studied in mammalian models, which have provided evidence on ACh production by immune cells (the noncholinergic neuronal system); however, these neuroimmunomodulation mechanisms in fish and lower vertebrates are poorly studied. Therefore, the objective of this review paper was to analyze the influence of the cholinergic system on the immune response of teleost fish, which could provide information concerning the possibility of bidirectional communication between the nervous and immune systems in these organisms and provide data for a better understanding of basic issues in neuroimmunology in lower vertebrates, such as bony fishes. Thus, the use of fish as a model in biomedical research may contribute to a better understanding of human diseases and diseases in other animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.