ReviewFrontiers in systems neuroscience2013
Functional and structural changes throughout the auditory system following congenital and early-onset deafness: implications for hearing restoration.
Review in Frontiers in systems neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Brain Morphological Modifications in Congenital and Acquired Auditory Deprivation: A Systematic Review and Coordinate-Based Meta-Analysis.Frontiers in neuroscience · 2022Pooled it
- Hierarchical Network Adaptations and Structure-Function Scaffolding in the Deaf Adult Brain.Brain topography · 2026Article
- Applications and Challenges of Auditory Brain-Computer Interfaces in Objective Auditory Assessments for Pediatric Cochlear Implants.Exploration (Beijing, China) · 2025Review
- Musical neurodynamics.Nature reviews. Neuroscience · 2025Review
- Cortical thickness differences between hearing and perinatally deaf cats using ultra-high field MRI.Neuroimage. Reports · 2024Article
- The brain can develop conflicting multisensory principles to guide behavior.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Experience-Dependent Plasticity in Nucleus Laminaris of the Barn Owl.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Against cortical reorganisation.eLife · 2023Article
- Pervasive cortical and white matter anomalies in a mouse model for CHARGE syndrome.Journal of anatomy · 2023Article
- The gradient in gray matter thickness across auditory cortex and differential cortical thickness changes following perinatal deafness.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- A review of the auditory-gut-brain axis.Frontiers in neuroscience · 2023Review
- Linking Cerebrovascular Dysfunction to Age-Related Hearing Loss and Alzheimer's Disease-Are Systemic Approaches for Diagnosis and Therapy Required?Biomolecules · 2022Review
- Article
- Audiovisual Integration for Saccade and Vergence Eye Movements Increases with Presbycusis and Loss of Selective Attention on the Stroop Test.Brain sciences · 2022Article
- The natural history of OTOF-related auditory neuropathy spectrum disorders: a multicenter study.Human genetics · 2022Article
- Central auditory deficits associated with genetic forms of peripheral deafness.Human genetics · 2022Review
- Estimating health of the implanted cochlea using psychophysical strength-duration functions and electrode configuration.Hearing research · 2022Article
- Functional Brain Connections Identify Sensorineural Hearing Loss and Predict the Outcome of Cochlear Implantation.Frontiers in computational neuroscience · 2022Article
- Cytoarchitectonic Maps of the Human Metathalamus in 3D Space.Frontiers in neuroanatomy · 2022Article
- Regulation of auditory plasticity during critical periods and following hearing loss.Hearing research · 2020Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The absence of auditory input, particularly during development, causes widespread changes in the structure and function of the auditory system, extending from peripheral structures into auditory cortex. In humans, the consequences of these changes are far-reaching and often include detriments to language acquisition, and associated psychosocial issues. Much of what is currently known about the nature of deafness-related changes to auditory structures comes from studies of congenitally deaf or early-deafened animal models. Fortunately, the mammalian auditory system shows a high degree of preservation among species, allowing for generalization from these models to the human auditory system. This review begins with a comparison of common methods used to obtain deaf animal models, highlighting the specific advantages and anatomical consequences of each. Some consideration is also given to the effectiveness of methods used to measure hearing loss during and following deafening procedures. The structural and functional consequences of congenital and early-onset deafness have been examined across a variety of mammals. This review attempts to summarize these changes, which often involve alteration of hair cells and supporting cells in the cochleae, and anatomical and physiological changes that extend through subcortical structures and into cortex. The nature of these changes is discussed, and the impacts to neural processing are addressed. Finally, long-term changes in cortical structures are discussed, with a focus on the presence or absence of cross-modal plasticity. In addition to being of interest to our understanding of multisensory processing, these changes also have important implications for the use of assistive devices such as cochlear implants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.