ArticleProceedings of the National Academy of Sciences of the United States of America2013
Genetic mapping of adaptation reveals fitness tradeoffs in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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78 citing papers in PubMed.
- Differentiation for drought strategy but conserved plasticity to heat and drought in locally adapted populations of Arabidopsis thaliana.Annals of botany · 2026Article
- MYB59 is Linked to Natural Variation of Water-Use Associated With Warmer Temperatures inPlant-environment interactions (Hoboken, N.J.) · 2026Article
- Differentiation for drought strategy but conserved plasticity to heat and drought in locally adapted populations ofbioRxiv : the preprint server for biology · 2026Article
- Genomic prediction of agronomic traits in perennial ryegrass (Lolium perenne L.) and genotype x environment interactions at the limit of the species distribution.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Advancing ecological and evolutionary research in Arabidopsis: Extending insights into model and nonmodel plants.The Plant cell · 2025Review
- Multiple independent MGR5 alleles contribute to a clinal pattern in leaf magnesium across the distribution of Arabidopsis thaliana.The New phytologist · 2025Article
- Genetic diversity and environmental adaptation in Ethiopian tef.G3 (Bethesda, Md.) · 2025Article
- Adaptation to soil type contributes little to local adaptation in an Italian and a Swedish ecotype ofBiology letters · 2024Article
- Temperature-dependent jumonji demethylase modulates flowering time by targeting H3K36me2/3 in Brassica rapa.Nature communications · 2024Article
- Biotic interactions promote local adaptation to soil in plants.Nature communications · 2024Article
- Current status of community resources and priorities for weed genomics research.Genome biology · 2024Review
- Low frequency of the wild-type freezing-tolerance LsCBF7 allele among lettuce population suggests a negative selection during domestication and breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Variation and plasticity in life-history traits and fitness of wild Arabidopsis thaliana populations are not related to their genotypic and ecological diversity.BMC ecology and evolution · 2024Article
- Flowering time: From physiology, through genetics to mechanism.Plant physiology · 2024Review
- Evaluating the Adaptive Fitness of Circadian Clocks and their Evolution.Journal of biological rhythms · 2024Review
- A large-effect fitness trade-off across environments is explained by a single mutation affecting cold acclimation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Pan-European study of genotypes and phenotypes in the Arabidopsis relative Cardamine hirsuta reveals how adaptation, demography, and development shape diversity patterns.PLoS biology · 2023Article
- Adaptive and maladaptive introgression in grapevine domestication.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Genomic analyses point to a low evolutionary potential of prospective source populations for assisted migration in a forest herb.Evolutionary applications · 2022Article
- Climate-Driven Adaptive Differentiation inGenes · 2022Article
18 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Organisms inhabiting different environments are often locally adapted, and yet despite a considerable body of theory, the genetic basis of local adaptation is poorly understood. Unanswered questions include the number and effect sizes of adaptive loci, whether locally favored loci reduce fitness elsewhere (i.e., fitness tradeoffs), and whether a lack of genetic variation limits adaptation. To address these questions, we mapped quantitative trait loci (QTL) for total fitness in 398 recombinant inbred lines derived from a cross between locally adapted populations of the highly selfing plant Arabidopsis thaliana from Sweden and Italy and grown for 3 consecutive years at the parental sites (>40,000 plants monitored). We show that local adaptation is controlled by relatively few genomic regions of small to modest effect. A third of the 15 fitness QTL we detected showed evidence of tradeoffs, which contrasts with the minimal evidence for fitness tradeoffs found in previous studies. This difference may reflect the power of our multiyear study to distinguish conditionally neutral QTL from those that reflect fitness tradeoffs. In Sweden, but not in Italy, the local genotype underlying fitness QTL was often maladaptive, suggesting that adaptation there is constrained by a lack of adaptive genetic variation, attributable perhaps to genetic bottlenecks during postglacial colonization of Scandinavia or to recent changes in selection regime caused by climate change. Our results suggest that adaptation to markedly different environments can be achieved through changes in relatively few genomic regions, that fitness tradeoffs are common, and that lack of genetic variation can limit adaptation.
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