Evidence map›Paper›PMID 24323894›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2014

Substrates with patterned extracellular matrix and subcellular stiffness gradients reveal local biomechanical responses.

Peter Tseng, Dino Di Carlo

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. In Situ Single-Cell Western Blot on Adherent Cell Culture.Angewandte Chemie (International ed. in English) · 2019
    Review
  5. Article
  6. Review
  7. Article
  8. 4-D Flow Control in Porous Scaffolds: Toward a Next Generation of Bioreactors.IEEE transactions on bio-medical engineering · 2017
    Article
  9. Vascular smooth muscle cell durotaxis depends on extracellular matrix composition.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  10. Flexible and stretchable micromagnet arrays for tunable biointerfacing.Advanced materials (Deerfield Beach, Fla.) · 2015
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter TsengDepartment of Bioengineering, University of California Los Angeles, 420 Westwood Plaza 5121 Engineering V, Los Angeles, CA, 90095, USA.
Dino Di Carlo

Funding

Engineering the Intracellular Micro- and NanoenvironmentDP2OD007113 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DI CARLO, DINO · 2010 to 2010
$2.3M
NIH HHS 1DP2OD007113NIH HHS DP2 OD007113
6 · The paper itself

Abstract

A substrate fabrication process is developed to pattern both the extracellular matrix (ECM) and rigidity at sub-cellular spatial resolution. When growing cells on these substrates, it is found that cells respond locally in their cytoskeleton assembly. The presented method allows unique insight into the biological interpretation of mechanical signals, whereas photolithography-based fabrication is amenable to integration with complex microfabricated substructures.

Indexed as

Culture MediaElasticityMicrotechnology3T3 CellsAcrylamideActinsAnimalsCell AdhesionCell Culture TechniquesCell ShapeCytoskeletonDimethylpolysiloxanesElastic ModulusEpoxy ResinsExtracellular MatrixFibroblastsAcrylamideActinsbaysilonblebbistatinCulture MediaDimethylpolysiloxanesEpoxy ResinsHeterocyclic Compounds, 4 or More RingsMyosin Type IIbiomechanicsBioMEMScell controlmechanotransductionstress fibers

Identifiers

PMID24323894
PMCPMC3947434

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.