Evidence map›Paper›PMID 24323635›Full record

ArticleThe Journal of general virology2014

Prevalence, genetic diversity and recombination of species G enteroviruses infecting pigs in Vietnam.

Nguyen Van Dung, Pham Hong Anh, Nguyen Van Cuong, Ngo Thi Hoa, Juan Carrique-Mas, Vo Be Hien, James Campbell, Stephen Baker, Jeremy Farrar, Mark E Woolhouse and 2 more

Abstract read
In one paragraph

Article in The Journal of general virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Swine polioencephalomyelitis in Brazil: identification of Teschovirus A, Sapelovirus A, and Enterovirus G in a farm from Southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  11. Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Teschovirus and other swine and human enteric viruses in Brazilian watersheds impacted by swine husbandry.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  17. Article
  18. Article
  19. Longitudinal survey of Teschovirus A, Sapelovirus A, and Enterovirus G fecal excretion in suckling and weaned pigs.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Nguyen Van DungInfection and Immunity Division, Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh EH25 9RG, UK.
Pham Hong AnhOxford University Clinical Research Unit, 764 Vo Van Kiet, W.1 Quan 5, Ho Chi Minh City, Vietnam.
Nguyen Van CuongOxford University Clinical Research Unit, 764 Vo Van Kiet, W.1 Quan 5, Ho Chi Minh City, Vietnam.
Ngo Thi HoaNuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.
Juan Carrique-MasOxford University Clinical Research Unit, 764 Vo Van Kiet, W.1 Quan 5, Ho Chi Minh City, Vietnam.
Vo Be HienSubdepartment of Animal Health, Dong Thap Province, Vietnam.
James CampbellOxford University Clinical Research Unit, 764 Vo Van Kiet, W.1 Quan 5, Ho Chi Minh City, Vietnam.
Stephen BakerLondon School of Hygiene and Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, UK.
Jeremy FarrarOxford University Clinical Research Unit, 764 Vo Van Kiet, W.1 Quan 5, Ho Chi Minh City, Vietnam.
Mark E WoolhouseCentre for Immunity, Infection and Evolution, University of Edinburgh, Ashworth Laboratories, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, UK.
Juliet E BryantNuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.
Peter SimmondsCentre for Immunity, Infection and Evolution, University of Edinburgh, Ashworth Laboratories, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, UK.
Oxford University Clinical Research Unit · VNCentre for Immunity, Infection and Evolution · GBRoslin Institute · GBUniversity of Edinburgh · GBUniversity of Oxford · GB

Funding

Wellcome Trust 093724Wellcome Trust 095831Wellcome Trust 100087Wellcome Trust WT/093724/Z/10/Z
6 · The paper itself

Abstract

Picornaviruses infecting pigs, described for many years as 'porcine enteroviruses', have recently been recognized as distinct viruses within three distinct genera (Teschovirus, Sapelovirus and Enterovirus). To better characterize the epidemiology and genetic diversity of members of the Enterovirus genus, faecal samples from pigs from four provinces in Vietnam were screened by PCR using conserved enterovirus (EV)-specific primers from the 5' untranslated region (5' UTR). High rates of infection were recorded in pigs on all farms, with detection frequencies of approximately 90% in recently weaned pigs but declining to 40% in those aged over 1 year. No differences in EV detection rates were observed between pigs with and without diarrhoea [74% (n = 70) compared with 72% (n = 128)]. Genetic analysis of consensus VP4/VP2 and VP1 sequences amplified from a subset of EV-infected pigs identified species G EVs in all samples. Among these, VP1 sequence comparisons identified six type 1 and seven type 6 variants, while four further VP1 sequences failed to group with any previously identified EV-G types. These have now been formally assigned as EV-G types 8-11 by the Picornavirus Study Group. Comparison of VP1, VP4/VP2, 3D(pol) and 5' UTRs of study samples and those available on public databases showed frequent, bootstrap-supported differences in their phylogenies indicative of extensive within-species recombination between genome regions. In summary, we identified extremely high frequencies of infection with EV-G in pigs in Vietnam, substantial genetic diversity and recombination within the species, and evidence for a much larger number of circulating EV-G types than currently described.

Indexed as

Genetic VariationRecombination, GeneticAnimalsEnteroviruses, PorcineEnterovirus InfectionsMolecular Sequence DataPhylogenyPrevalenceSus scrofaSwineSwine DiseasesVietnamViral ProteinsViral Proteins

Identifiers

PMID24323635
PMCPMC4029279
OpenAlexW2089162394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.