ArticleJournal of experimental botany2014
The heat shock factor family from Triticum aestivum in response to heat and other major abiotic stresses and their role in regulation of heat shock protein genes.
Article in Journal of experimental botany, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 1 of them a synthesis that pooled it.
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134 citing papers in PubMed, 1 synthesis or guideline pooled it, 254 citations in OpenAlex.
- Pooled it
- Heat stress responses of plants during adaptation to high temperature environments: A review of recent advances and insights.Plant signaling & behavior · 2026Review
- Harnessing genomics approaches for heat stress resilience in wheat: from discovery to deployment.Journal of experimental botany · 2026Review
- Genome-wide identification of Hsf gene family in citrus and functional analysis of CsHsfA1a in heat stress response.Plant cell reports · 2026Article
- Genome-Wide Identification and Systematic Analysis of theInternational journal of molecular sciences · 2026Article
- Integrative characterization of the heat shock transcription factors inFrontiers in plant science · 2026Article
- Genome-Wide Analysis ofFood science & nutrition · 2026Article
- Review
- ThePlants (Basel, Switzerland) · 2025Article
- Multi-omic profiles of Sorghum genotypes with contrasting heat tolerance connect pathways related to thermotolerance.Journal of experimental botany · 2025Article
- An ABF5b-HsfA2h/HsfC2a-NCED2b/POD4/HSP26 module integrates multiple signaling pathway to modulate heat stress tolerance in wheat.Plant biotechnology journal · 2025Article
- Article
- Replacement of chromosome 3D with Thinopyrum chromosome 3St led to increased drought tolerance during the flowering stage in wheat.Plant cell reports · 2025Article
- PtHSF5, a HSF transcription factor from Pinellia Ternata positively regulates heat tolerance in Arabidopsis.BMC plant biology · 2025Article
- Article
- Transcriptomic Identification of Key Genes Responding to High Heat Stress in Moso Bamboo (Genes · 2025Article
- Heat shock factor ZmHsf17 positively regulates phosphatidic acid phosphohydrolase ZmPAH1 and enhances maize thermotolerance.Journal of experimental botany · 2025Article
- Vegetal memory through the lens of transcriptomic changes - recent progress and future practical prospects for exploiting plant transcriptional memory.Plant signaling & behavior · 2024Review
- Genome-Wide Identification and Expression Analysis of theCurrent issues in molecular biology · 2024Article
- The MdHSC70-MdWRKY75 module mediates basal apple thermotolerance by regulating the expression of heat shock factor genes.The Plant cell · 2024Article
74 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat shock factors (Hsfs) play a central regulatory role in acquired thermotolerance. To understand the role of the major molecular players in wheat adaptation to heat stress, the Hsf family was investigated in Triticum aestivum. Bioinformatic and phylogenetic analyses identified 56 TaHsf members, which are classified into A, B, and C classes. Many TaHsfs were constitutively expressed. Subclass A6 members were predominantly expressed in the endosperm under non-stress conditions. Upon heat stress, the transcript levels of A2 and A6 members became the dominant Hsfs, suggesting an important regulatory role during heat stress. Many TaHsfA members as well as B1, C1, and C2 members were also up-regulated during drought and salt stresses. The heat-induced expression profiles of many heat shock protein (Hsp) genes were paralleled by those of A2 and A6 members. Transactivation analysis revealed that in addition to TaHsfA members (A2b and A4e), overexpression of TaHsfC2a activated expression of TaHsp promoter-driven reporter genes under non-stress conditions, while TaHsfB1b and TaHsfC1b did not. Functional heat shock elements (HSEs) interacting with TaHsfA2b were identified in four TaHsp promoters. Promoter mutagenesis analysis demonstrated that an atypical HSE (GAACATTTTGGAA) in the TaHsp17 promoter is functional for heat-inducible expression and transactivation by Hsf proteins. The transactivation of Hsp promoter-driven reporter genes by TaHsfC2a also relied on the presence of HSE. An activation motif in the C-terminal domain of TaHsfC2a was identified by amino residue substitution analysis. These data demonstrate the role of HsfA and HsfC2 in regulation of Hsp genes in wheat.
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