ArticleEnvironmental science and pollution research international2014
Histopathological and ultrastructural perturbations in tilapia liver as potential indicators of pollution in Lake Al-Asfar, Saudi Arabia.
Article in Environmental science and pollution research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 citing papers in PubMed, 23 citations in OpenAlex.
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- Toxic effects of copper on liver and cholinesterase of Clarias gariepinus.Environmental science and pollution research international · 2017Article
- Alleviative effect of selenium on inflammatory damage caused by lead via inhibiting inflammatory factors and heat shock proteins in chicken testes.Environmental science and pollution research international · 2017Article
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Authors and funding
1 author at 1 institution in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Lake Al-Asfar (Al-Hassa, Saudi Arabia) is under threat from contaminants released through human activities such as agriculture and urban and industrial developments. In the present study, histopathologic and ultrastructural changes in liver of tilapia Oreochromis niloticus were analyzed to monitor the possible impact of pollution in Al-Asfar estuary. Heavy metals such as Ni, Fe, Zn, Co, Ba, Pb, and Cd were predominant in the lake water and far exceeded the international permissible limits. In fish samples, high prevalences of preneoplastic changes (50 %) and one case of cholangiocarcinoma were revealed in liver tissues. Cytological damage in fish hepatocytes included glycogen exhaustion, deformation of nuclear envelope, heterochromatin condensation, mitochondrial degeneration, vesiculation of rough endoplasmic reticulum, augmentation of smooth endoplasmic reticulum, and lysosomal proliferation. In conclusion, the observed biomarker responses were potential indicators of health impairment or disease in field fish populations, although there was no direct proof of a simple cause-effect relationship. This is the first biological effect assessment in Lake Al-Asfar using tilapia as suitable target species.
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