Newborns, one of the last therapeutic orphans to be adopted.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Enabling evidence generation for extremely preterm neonates: the use of neonatal real-world data.Pediatric research · 2026
   Review
2. Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias.Frontiers in pharmacology · 2024
   Review
3. Innovative approaches and recent advances in the study of ontogeny of drug metabolism and transport.British journal of clinical pharmacology · 2022
   Review
4. Parental perspectives long term after neonatal clinical trial participation: a survey.Trials · 2020
   Article
5. The Utility of Pharmacometric Models in Clinical Pharmacology Research in Infants.Current pharmacology reports · 2020
   Article
6. Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs.Pharmaceutics · 2020
   Article
7. Standardizing Safety Assessment and Reporting for Neonatal Clinical Trials.The Journal of pediatrics · 2020
   Article
8. Issues, challenges, and the way forward in conducting clinical trials among neonates: investigators' perspective.Journal of perinatology : official journal of the California Perinatal Association · 2019
   Article
9. Outcomes Research in Vulnerable Pediatric Populations.Journal of neurosurgical anesthesiology · 2019
   Review
10. The Need for Pediatric Drug Development.The Journal of pediatrics · 2018
    Article
11. Newborns still lack drug data to guide therapy.British journal of clinical pharmacology · 2016
    Article
12. Neonates and medicines: a roadmap to further improve neonatal pharmaceutical care.European journal of pediatrics · 2016
    Article
13. Challenges Associated with Route of Administration in Neonatal Drug Delivery.Clinical pharmacokinetics · 2016
    Review
14. Neonatal drug therapy: The first frontier of therapeutics for children.Clinical pharmacology and therapeutics · 2015
    Review
15. Drug-induced renal damage in preterm neonates: state of the art and methods for early detection.Drug safety · 2015
    Review

Corrections and comments

• Comment on
  Drug labeling and exposure in neonates.2014

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as