ArticleJournal of genetic counseling2014
Perceived risk following melanoma genetic testing: a 2-year prospective study distinguishing subjective estimates from recall.
Article in Journal of genetic counseling, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 31 citations in OpenAlex.
- Examining strategies for addressing high levels of 'I don't know' responding to risk perception questions for colorectal cancer and diabetes: an experimental investigation.Psychology & health · 2021Trial
- Differences in skin cancer-related beliefs and psychological distress among adults living in Florida who do and do not report a sunburn.Preventive medicine reports · 2026Article
- The Family Lifestyles, Actions and Risk Education (FLARE) study: Protocol for a randomized controlled trial of a sun protection intervention for children of melanoma survivors.Contemporary clinical trials · 2023Article
- Testing Explanations for Skepticism of Personalized Risk Information.Medical decision making : an international journal of the Society for Medical Decision Making · 2023Article
- Priority of Risk (But Not Perceived Magnitude of Risk) Predicts Improved Sun-Protection Behavior Following Genetic Counseling for Familial Melanoma.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021Article
- The Melanoma Genomics Managing Your Risk Study randomised controlled trial: statistical analysis plan.Trials · 2020Article
- A primer in genomics for social and behavioral investigators.Translational behavioral medicine · 2020Article
- Article
- Differences in reported sun protection practices, skin cancer knowledge, and perceived risk for skin cancer between rural and urban high school students.Cancer causes & control : CCC · 2019Article
- Genetic counseling, genetic testing, and risk perceptions for breast and colorectal cancer: Results from the 2015 National Health Interview Survey.Preventive medicine · 2019Article
- Risk perception before and after presymptomatic genetic testing for Huntington's disease: Not always what one might expect.Molecular genetics & genomic medicine · 2018Article
- A novel educational intervention targeting melanoma risk and prevention knowledge among children with a familial risk for melanoma.Patient education and counseling · 2018Article
- Genetic test reporting of CDKN2A provides informational and motivational benefits for managing melanoma risk.Translational behavioral medicine · 2018Article
- Article
- Pediatric Predispositional Genetic Risk Communication: Potential Utility for Prevention and Control of Melanoma Risk as an Exemplar.Journal of genetic counseling · 2017Article
- A Qualitative Study to Explore the Views and Attitudes towards Prenatal Testing in Adults Who Have Muenke Syndrome and their Partners.Journal of genetic counseling · 2017Article
- Genomic Information may Inhibit Weight-Related Behavior Change Inclinations Among Individuals in a Fear State.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2016Article
- The role of conviction in personal disease risk perceptions: What can we learn from research on attitude strength?Social and personality psychology compass · 2016Article
- Discussion of photoprotection, screening, and risk behaviors with children and grandchildren after melanoma genetic testing.Journal of community genetics · 2016Article
- Impact of melanoma genetic test reporting on perceived control over melanoma prevention.Journal of behavioral medicine · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
A major goal of predictive genetic testing is to alert people to their risk before illness onset; however, little is known about how risk perceptions change following genetic testing and whether information is recalled accurately over time. In the United States, a CDKN2A/p16 mutation confers 76 % lifetime risk of melanoma. Following genetic counseling and test reporting, subjective risk estimates and recall of counselor-provided risk estimates were assessed 5 times over the next 2 years among 60 adult members of 2 extended CDKN2A/p16 kindreds. No sustained changes from baseline in risk perceptions were reported. Unaffected carriers (n = 15) consistently reported significantly lower subjective risk estimates (46 %) than they were actually given (76 %, p < 0.001) or recalled having been given (60 %, p < 0.001). Noncarriers' (n = 27) risk estimates decreased following results disclosure, but rebounded, with both subjective and recalled estimates subsequently exceeding what they were told by the counselor (both ps < 0.001). Affected carriers' (n = 18) risk estimates for developing a new melanoma corresponded well to counselor-provided information (p = 0.362). For all 3 patient groups, results were consistent across multiple risk measures and remained similar when demographic, phenotypic, and baseline behavioral contributors to melanoma risk were statistically controlled. These findings are consistent with other studies of risk perception, but additional studies of more diverse populations are needed to understand the reasons behind both the persistence of initial risk estimates and their divergence from information provided by the counselor during genetic counseling. Additionally, determining whether holding subjective risk perceptions that differ from counselor-provided information ultimately affects adherence to management recommendations will help guide the presentation of risk information in genetic counseling practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.