ArticleOptics letters2013
Comparison of line-scanned and point-scanned dual-axis confocal microscope performance.
Article in Optics letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Miniature line-scanned dual-axis confocal microscope for versatile clinical use.Biomedical optics express · 2023Article
- Miniature side-view dual axes confocal endomicroscope for repetitive in vivo imaging.Biomedical optics express · 2023Article
- Performance tradeoffs for single- and dual-objective open-top light-sheet microscope designs: a simulation-based analysis.Biomedical optics express · 2020Article
- Label-free in vivo pathology of human epithelia with a high-speed handheld dual-axis confocal microscope.Journal of biomedical optics · 2019Article
- Handheld line-scanned dual-axis confocal microscope with pistoned MEMS actuation for flat-field fluorescence imaging.Optics letters · 2019Article
- Line-scanning hyperspectral imaging based on structured illumination optical sectioning.Biomedical optics express · 2017Article
- Optical-sectioning microscopy of protoporphyrin IX fluorescence in human gliomas: standardization and quantitative comparison with histology.Journal of biomedical optics · 2017Article
- Bessel-beam illumination in dual-axis confocal microscopy mitigates resolution degradation caused by refractive heterogeneities.Journal of biophotonics · 2017Article
- Miniature in vivo MEMS-based line-scanned dual-axis confocal microscope for point-of-care pathology.Biomedical optics express · 2016Article
- Assessing the imaging performance of light sheet microscopies in highly scattering tissues.Biomedical optics express · 2016Article
- Video-rate in vivo fluorescence imaging with a line-scanned dual-axis confocal microscope.Journal of biomedical optics · 2015Article
- Comparing high-resolution microscopy techniques for potential intraoperative use in guiding low-grade glioma resections.Lasers in surgery and medicine · 2015Article
- Characterizing the beam steering and distortion of Gaussian and Bessel beams focused in tissues with microscopic heterogeneities.Biomedical optics express · 2015Article
- Sheet-scanned dual-axis confocal microscopy using Richardson-Lucy deconvolution.Optics letters · 2014Article
- Full-field interferometric confocal microscopy using a VCSEL array.Optics letters · 2014Article
- Modulated-alignment dual-axis (MAD) confocal microscopy for deep optical sectioning in tissues.Biomedical optics express · 2014Article
- Dual-axis confocal microscopy for point-of-care pathology.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The point-scanned dual-axis confocal (PS-DAC) microscope has been shown to exhibit superior capability to reject out-of-focus and multiply scattered light in comparison to its conventional single-axis counterpart. However, the slow frame rate (typically <5 Hz) resulting from point-by-point data collection makes these systems vulnerable to motion artifacts. While video-rate point-scanned confocal microscopy is possible, a line-scanned dual-axis confocal (LS-DAC) microscope provides a simpler means of achieving high-speed imaging through line-by-line data collection, but sacrifices contrast due to loss of confocality along one dimension. Here we evaluate the performance trade-offs between an LS-DAC and PS-DAC microscope with identical spatial resolutions. Characterization experiments of the LS-DAC and PS-DAC microscopes with tissue phantoms, in reflectance mode, are shown to match results from Monte Carlo scattering simulations of the systems. Fluorescence images of mouse brain vasculature, obtained using resolution-matched LS-DAC and PS-DAC microscopes, demonstrate the comparable performance of LS-DAC and PS-DAC microscopy at shallow depths.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.