Evidence map›Paper›PMID 24321308›Full record

ArticleTheoretical population biology2014

Within a sample from a population, the distribution of the number of descendants of a subsample's most recent common ancestor.

John L Spouge

Abstract read
In one paragraph

Article in Theoretical population biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John L SpougeBuilding 38A, Room 6N603, National Center for Biotechnology Information, Bethesda MD 20894, United States. Electronic address: spouge@ncbi.nlm.nih.gov.

Funding

Statistics and Algorithms in EvolutionZIALM201008 · NLM · NATIONAL LIBRARY OF MEDICINE · PI SPOUGE, JOHN · 2010 to 2019
$1.6M
Intramural NIH HHS ZIA LM201008
6 · The paper itself

Abstract

Sample n individuals uniformly at random from a population, and then sample m individuals uniformly at random from the sample. Consider the most recent common ancestor (MRCA) of the subsample of m individuals. Let the subsample MRCA have j descendants in the sample (m ⩽ j ⩽ n). Under a Moran or coalescent model (and therefore under many other models), the probability that j = n is known. In this case, the subsample MRCA is an ancestor of every sampled individual, and the subsample and sample MRCAs are identical. The probability that j = m is also known. In this case, the subsample MRCA is an ancestor of no sampled individual outside the subsample. This article derives the complete distribution of j, enabling inferences from the corresponding p-value. The text presents hypothetical statistical applications pertinent to taxonomy (the gene flow between Neanderthals and anatomically modern humans) and medicine (the association of genetic markers with disease).

Indexed as

Genetics, PopulationModels, TheoreticalCoalescent theoryMost recent common ancestor of a subsample

Identifiers

PMID24321308
PMCPMC3944932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.