Observational studyBMC pulmonary medicine2013
"Causes of death in asthma, COPD and non-respiratory hospitalized patients: a multicentric study".
Observational study in BMC pulmonary medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2022Pooled it
- The association between asthma and heart failure - a systematic review and meta-analysis.European clinical respiratory journal · 2026Review
- COVID-19 and Long-term Risk of Ischemic Heart Disease in Asthma.Allergy, asthma & immunology research · 2025Article
- Exploring the association between asthma and chronic comorbidities: impact on clinical outcomes.Frontiers in medicine · 2024Review
- Machine-learning algorithms for asthma, COPD, and lung cancer risk assessment using circulating microbial extracellular vesicle data and their application to assess dietary effects.Experimental & molecular medicine · 2022Article
- Hospitalization and mortality for acute exacerbation of asthma: an Italian population-based study.Internal and emergency medicine · 2022Article
- Burden and impact of arrhythmias in asthma-related hospitalizations: Insight from the national inpatient sample.Journal of arrhythmia · 2021Article
- Journal Club: Do Inhaled Corticosteroids Reduce All-Cause Mortality in Chronic Obstructive Pulmonary Disease? What is the Latest Evidence?Chronic obstructive pulmonary diseases (Miami, Fla.) · 2021Article
- Health risks in the cleaning industry: a Belgian census-linked mortality study (1991-2011).International archives of occupational and environmental health · 2018Article
- Putative Role of Cardio Metabolic Risk Among Poorly Controlled Asthmatics in South Indian Population.Indian journal of clinical biochemistry : IJCB · 2017Article
- Our paper 20 years later: the unfulfilled promises of nebulised adrenaline in acute severe asthma.Intensive care medicine · 2016Article
- ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing.BMJ open respiratory research · 2016Article
- Self-reported symptoms of chronic cough and breathlessness in working-age men in the city of Izhevsk, Russia: associations with cardiovascular disease risk factors and comorbidities.BMJ open respiratory research · 2015Article
- Causes of death in patients with asthma and asthma-chronic obstructive pulmonary disease overlap syndrome.International journal of chronic obstructive pulmonary disease · 2015Article
- Respiratory Pathology and Cardiovascular Diseases: A Scoping Review.Open respiratory archivesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited information on the causes of death in asthma patients.To determine the causes of death in hospitalized asthmatic patients and to compare with those observed in COPD patients and non-respiratory individuals, with a particular interest in associations with previous cardiovascular disease.
methodsRetrospective case-control study which analyzed the deaths of all hospitalized patients admitted for any reason during January, April, July and October of 2008 in 13 Spanish centers. Medical records of deceased patients were reviewed, and demographic and clinical data were collected.
resultsA total of 2,826 deaths (mean age 75 years, 56% men) were included in the analysis, of which 82 (2.9%) were of patients with asthma and 283 (10%) with COPD.The most common causes of death in asthma patients were cardiovascular diseases (29.3%), malignancies (20.7%) and infections (14.6%); in COPD patients they were malignancies (26.5%), acute respiratory failure (25.8%) and cardiovascular diseases (21.6%). Asthma, compared to COPD patients, died significantly less frequently from acute respiratory failure and lung cancer. A multivariate logistic regression analysis failed to associate asthma with cardiovascular deaths.
conclusionsCardiovascular disease is the most frequent cause of death among hospitalized asthma patients. The specific causes of death differ between asthma and COPD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.