Evidence map›Paper›PMID 24321170›Full record

ArticleJournal of biomedical informatics2014

Development of a clinician reputation metric to identify appropriate problem-medication pairs in a crowdsourced knowledge base.

Allison B McCoy, Adam Wright, Deevakar Rogith, Safa Fathiamini, Allison J Ottenbacher, Dean F Sittig

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Allison B McCoyThe University of Texas School of Biomedical Informatics at Houston, 7000 Fannin St., Ste. 600, Houston, TX 70030, USA. Electronic address: amccoy1@tulane.edu.
Adam WrightBrigham and Women's Hospital, Harvard Medical School, 1620 Tremont St., Boston, MA 02115, USA. Electronic address: awright5@partners.org.
Deevakar RogithThe University of Texas School of Biomedical Informatics at Houston, 7000 Fannin St., Ste. 600, Houston, TX 70030, USA. Electronic address: deevakar.rogith@uth.tmc.edu.
Safa FathiaminiThe University of Texas School of Biomedical Informatics at Houston, 7000 Fannin St., Ste. 600, Houston, TX 70030, USA. Electronic address: safa.fathiamini@uth.tmc.edu.
Allison J OttenbacherThe University of Texas Medical School at Houston, 6410 Fannin St., Ste. 1100, Houston, TX 77030, USA. Electronic address: allison.ottenbacher@nih.gov.
Dean F SittigThe University of Texas School of Biomedical Informatics at Houston, 7000 Fannin St., Ste. 600, Houston, TX 70030, USA. Electronic address: dean.f.sittig@uth.tmc.edu.
The University of Texas Health Science Center at Houston · USThe University of Texas Health Science Center · USBrigham and Women's Hospital · US

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Center for Clinical and Translational Sciences (CCTS)KL2TR000370 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$4.3M
InSPECt: Interactive Surveillance Portal for Evaluating Clinical supportK22LM011430 · NLM · TULANE UNIVERSITY OF LOUISIANA · PI MCCOY, ALLISON B · 2013 to 2015
$372k
NCATS NIH HHS KL2 TR000370NCATS NIH HHS KL2 TR 000370-06A1NCATS NIH HHS UL1 TR000371NCRR NIH HHS 3UL1RR024148NCRR NIH HHS UL1 RR024148NLM NIH HHS K22 LM011430
6 · The paper itself

Abstract

backgroundCorrelation of data within electronic health records is necessary for implementation of various clinical decision support functions, including patient summarization. A key type of correlation is linking medications to clinical problems; while some databases of problem-medication links are available, they are not robust and depend on problems and medications being encoded in particular terminologies. Crowdsourcing represents one approach to generating robust knowledge bases across a variety of terminologies, but more sophisticated approaches are necessary to improve accuracy and reduce manual data review requirements.

objectiveWe sought to develop and evaluate a clinician reputation metric to facilitate the identification of appropriate problem-medication pairs through crowdsourcing without requiring extensive manual review. APPROACH: We retrieved medications from our clinical data warehouse that had been prescribed and manually linked to one or more problems by clinicians during e-prescribing between June 1, 2010 and May 31, 2011. We identified measures likely to be associated with the percentage of accurate problem-medication links made by clinicians. Using logistic regression, we created a metric for identifying clinicians who had made greater than or equal to 95% appropriate links. We evaluated the accuracy of the approach by comparing links made by those physicians identified as having appropriate links to a previously manually validated subset of problem-medication pairs.

resultsOf 867 clinicians who asserted a total of 237,748 problem-medication links during the study period, 125 had a reputation metric that predicted the percentage of appropriate links greater than or equal to 95%. These clinicians asserted a total of 2464 linked problem-medication pairs (983 distinct pairs). Compared to a previously validated set of problem-medication pairs, the reputation metric achieved a specificity of 99.5% and marginally improved the sensitivity of previously described knowledge bases.

conclusionA reputation metric may be a valuable measure for identifying high quality clinician-entered, crowdsourced data.

Indexed as

Electronic Health RecordsKnowledge BasesMedical Records Systems, ComputerizedCrowdsourcingHumansInternetLogistic ModelsMedical InformaticsPharmaceutical PreparationsPhysiciansReproducibility of ResultsSoftwareUser-Computer InterfacePharmaceutical PreparationsCrowdsourcingElectronic health recordsKnowledge basesMedical recordsProblem-oriented

Identifiers

PMID24321170
PMCPMC4026169
OpenAlexW2152290993

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.