ReviewFrontiers in immunology2013
An updated view of the intracellular mechanisms regulating cross-presentation.
Review in Frontiers in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 57 citations in OpenAlex.
- Cross-Presentation and Activation of CD8+ T Cells: The Role of Pannexin-1 in Dendritic Cells.International journal of molecular sciences · 2026Article
- Different routes of MHC-I delivery to phagosomes and their consequences to CD8 T cell immunity.Seminars in immunology · 2023Review
- Sec22b-dependent antigen cross-presentation is a significant contributor of T cell priming during infection with the parasiteFrontiers in cell and developmental biology · 2023Article
- Using Self-Assembling ADDomer Platform to Display B and T Epitopes of Type O Foot-and-Mouth Disease Virus.Viruses · 2022Article
- Antigen Presentation in the Lung.Frontiers in immunology · 2022Review
- Review
- A Comprehensive Experimental Guide to Studying Cross-Presentation in Dendritic Cells In Vitro.Current protocols in immunology · 2020Article
- Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy.Pharmaceutics · 2020Review
- Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells.The Journal of experimental medicine · 2019Article
- Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8Frontiers in immunology · 2019Article
- Regulation of the Cell Biology of Antigen Cross-Presentation.Annual review of immunology · 2018Review
- Sipuleucel-T for the treatment of prostate cancer: novel insights and future directions.Future oncology (London, England) · 2018Review
- Exosomes from antigen-pulsed dendritic cells induce stronger antigen-specific immune responses than microvesicles in vivo.Scientific reports · 2017Article
- VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release.European journal of cell biology · 2017Article
- Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation.Journal of visualized experiments : JoVE · 2017Article
- A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation.Cell reports · 2017Article
- Card9 controls Dectin-1-induced T-cell cytotoxicity and tumor growth in mice.European journal of immunology · 2017Article
- Dying cells actively regulate adaptive immune responses.Nature reviews. Immunology · 2017Review
- Endogenous and tumour-derived microRNAs regulate cross-presentation in dendritic cells and consequently cytotoxic T cell function.Cytotechnology · 2016Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cross-presentation involves the presentation of peptides derived from internalized cargo on major histocompatibility complex class I molecules by dendritic cells, a process critical for tolerance and immunity. Detailed studies of the pathways mediating cross-presentation have revealed that this process takes place in a specialized subcellular compartment with a unique set of proteins. In this review, we focus on the recently appreciated role for intracellular vesicular traffic, which serves to equip compartments such as endosomes and phagosomes with the necessary apparatus for conducting the various steps of cross-presentation. We also consider how these pathways may integrate with inflammatory signals particularly from pattern recognition receptors that detect the presence of microbial components during infection. We discuss the consequences of such signals on initiating cross-presentation to stimulate adaptive CD8 T cell responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.