ArticleTheScientificWorldJournal2013
Nexfin noninvasive continuous hemodynamic monitoring: validation against continuous pulse contour and intermittent transpulmonary thermodilution derived cardiac output in critically ill patients.
Article in TheScientificWorldJournal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04911985 (Appraisal of the Exactness of a Method to Semiinvasively Evaluate the Cardiac Output of ICU-Patients Through the Use of the Pulsioflex Device), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Appraisal of the Exactness of a Method to Semiinvasively Evaluate the Cardiac Output of ICU-Patients Through the Use of the Pulsioflex Device
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of Pulse Indicator Continuous Cardiac Output Monitoring on Septic Shock Patients: A Meta-Analysis.Computational and mathematical methods in medicine · 2022Pooled it
- [Meta-analyses on measurement precision of non-invasive hemodynamic monitoring technologies in adults].Der Anaesthesist · 2018Pooled it
- The effect of plasma versus crystalloids on intravascular volume, tissue perfusion and tissue oxygenation: a randomized controlled trial in a human endotoxemia model.Critical care (London, England) · 2026Trial
- Noninvasive pulse contour analysis for determination of cardiac output in patients with chronic heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Trial
- Microcirculatory response and leukocyte activation in patients undergoing elective cardiac surgery with cardiopulmonary bypass.Journal of intensive medicine · 2026Article
- Durable insulin elimination after duodenal re-cellularization via electroporation therapy combined with glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes.iGIE : innovation, investigation and insights · 2025Article
- Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers.Intensive care medicine experimental · 2024Article
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- The identification of blood pressure variation with hypovolemia based on the volume compensation method.Frontiers in physiology · 2023Article
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- Non-invasive continuous blood pressure monitoring using the ClearSight system for pregnant women at high risks of post-partum hemorrhage: comparison with invasive blood pressure monitoring during cesarean section.Obstetrics & gynecology science · 2022Article
- Immediate reduction in left ventricular ejection time following TAVI is associated with improved quality of life.Frontiers in cardiovascular medicine · 2022Article
- Non-Invasive Continuous Measurement of Haemodynamic Parameters-Clinical Utility.Journal of clinical medicine · 2021Review
- Accuracy of non-invasive and minimally invasive hemodynamic monitoring: where do we stand?Annals of translational medicine · 2019Review
- Accuracy of the ClearSight™ system in patients undergoing abdominal aortic aneurysm surgery.Journal of anesthesia · 2019Article
- Warm water immersion in patients with chronic heart failure: a pilot study : Shah immerse: HF.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Sodium nitroprusside dilates cerebral vessels and enhances internal carotid artery flow in young men.The Journal of physiology · 2018Article
- A mesenteric traction syndrome affects near-infrared spectroscopy evaluated cerebral oxygenation because skin blood flow increases.Journal of clinical monitoring and computing · 2018Observational
- Baseline aortic pulse wave velocity is associated with central and peripheral pressor responses during the cold pressor test in healthy subjects.Physiological reports · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNexfin (Bmeye, Amsterdam, Netherlands) is a noninvasive cardiac output (CO) monitor based on finger arterial pulse contour analysis. The aim of this study was to validate Nexfin CO (NexCO) against thermodilution (TDCO) and pulse contour CO (CCO) by PiCCO (Pulsion Medical Systems, Munich, Germany). PATIENTS AND
methodsIn a mix of critically ill patients (n = 45), NexCO and CCO were measured continuously and recorded at 2-hour intervals during the 8-hour study period. TDCO was measured at 0-4-8 hrs.
resultsNexCO showed a moderate to good (significant) correlation with TDCO (R (2) 0.68, P < 0.001) and CCO (R (2) 0.71, P < 0.001). Bland and Altman analysis comparing NexCO with TDCO revealed a bias (± limits of agreement, LA) of 0.4 ± 2.32 L/min (with 36% error) while analysis comparing NexCO with CCO showed a bias (±LA) of 0.2 ± 2.32 L/min (37% error). NexCO is able to follow changes in TDCO and CCO during the same time interval (level of concordance 89.3% and 81%). Finally, polar plot analysis showed that trending capabilities were acceptable when changes in NexCO (ΔNexCO) were compared to ΔTDCO and ΔCCO (resp., 89% and 88.9% of changes were within the level of 10% limits of agreement).
conclusionwe found a moderate to good correlation between CO measurements obtained with Nexfin and PiCCO.
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