ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2014
Quality of life assessed with EQ-5D in patients undergoing glioma surgery: what is the responsiveness and minimal clinically important difference?
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 6 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- A systematic review of minimum important changes for generic multi-attribute utility instruments and recommendations for their estimation.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Pooled it
- How is the minimal clinically important difference established in health-related quality of life instruments? Review of anchors and methods.Health and quality of life outcomes · 2020Pooled it
- Quality-adjusted life years in glioma patients: a systematic review on currently available data and the lack of evidence-based utilities.Journal of neuro-oncology · 2019Pooled it
- Prevalence of symptoms in glioma patients throughout the disease trajectory: a systematic review.Journal of neuro-oncology · 2018Pooled it
- Impaired health-related quality of life in meningioma patients-a systematic review.Neuro-oncology · 2017Pooled it
- Can The EQ-5D Detect Meaningful Change? A Systematic Review.PharmacoEconomics · 2015Pooled it
- Cancer-specific utility: clinical validation of the EORTC QLU-C10D in patients with glioblastoma.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Trial
- Prospective inter-individual analysis of quality-adjusted life years (QALYs) in brain tumor patients: A comprehensive assessment of health preferences.International journal of cancer · 2026Article
- Review
- Sex differences in joint pain, limb function and quality of life among patients with Kashin-Beck disease in Northwest China.BMC musculoskeletal disorders · 2025Article
- Minimal clinically important difference of EQ-5D-5L, SF-6Dv2, and QLU-C10D in hematologic malignancy patients in China.Health and quality of life outcomes · 2025Article
- Validation of EuroQol instruments in paediatric patients and their caregivers in China: protocol for a prospective observational study.BMJ open · 2025Article
- Associations between financial toxicity, health-related quality of life, and well-being in Indonesian patients with breast cancer.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Review
- Responsiveness and minimal clinically important differences of the Trunk Assessment Scale for Spinal Cord injury (TASS).The journal of spinal cord medicine · 2025Article
- The EORTC QLU-C10D is a valid cancer-specific preference-based measure for cost-utility and health technology assessment in the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- Minimal Clinically Important Differences With the Outcomes of the App-Based Japanese Allergic Conjunctival Diseases Quality of Life Questionnaire: Cross-Sectional Observational Study.JMIR formative research · 2024Observational
- Incidence, risk factors, and clinical implications of postoperative blood in or near the resection cavity after glioma surgery.Brain & spine · 2024Article
- The minimal clinically important difference of app-based electronic patient-reported outcomes for hay fever.Clinical and translational allergy · 2023Article
- Change in four measures of physical function among older adults during lung cancer treatment: A mixed methods cohort study.Journal of geriatric oncology · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
purposeTo evaluate the responsiveness of EQ-5D 3L in patients undergoing intracranial glioma surgery and estimate the minimal clinically important difference (MCID). MATERIALS AND
methodsEQ-5D 3L index values from 164 patients who underwent glioma surgery in the period 2007-2012 were analysed. Responsiveness and MCID were estimated using a combination of distribution-based and anchor-based methods. Karnofsky performance status served as an anchor.
resultsPatients who improved functionally did not report significantly higher EQ-5D 3L scores post operatively with a standardized response mean (SRM) of 0.04 (p = 0.13). Patients who deteriorated functionally reported significantly lower EQ-5D 3L scores post operatively with a SRM of 0.72 (p < 0.001). With different approaches, we determined a range of MCID values from 0.13 to 0.15.
conclusionsEQ-5D 3L is responsive to changes when glioma patients are deteriorating functionally after surgery but not responsive when the patients are improving. The MCID values for EQ-5D 3L in glioma surgery seem higher than reported MCID values for other types of cancers.
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