Evidence map›Paper›PMID 24317968›Full record

Trial reportJournal of cancer survivorship : research and practice2014

Musculoskeletal changes after 1 year of exercise in older breast cancer survivors.

Jessica Dobek, Kerri M Winters-Stone, Jill A Bennett, Lillian Nail

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of cancer survivorship : research and practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00591747 (Strength Training for Older Breast Cancer Survivors), which is not on this map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00591747 nacompletednot on this map

Strength Training for Older Breast Cancer Survivors

TypeinterventionalSponsorOHSU Knight Cancer InstituteRan2005 to 2011Enrolled106ConditionsBreast Neoplasm, Osteoporosis, PostmenopausalArmsResistance Exercise, Flexibility Training
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Physical activity for women with breast cancer after adjuvant therapy.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Article
  10. Applying pre-participation exercise screening to breast cancer survivors: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  11. Article
  12. Exercise after breast cancer treatment: current perspectives.Breast cancer (Dove Medical Press) · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica DobekSchool of Nursing, Oregon Health and Science University, 3455 SW US Veteran's Hospital Rd, Mailcode: SN-ORD, Portland, OR, 97239, USA, carmonaj@ohsu.edu.
Kerri M Winters-Stone
Jill A Bennett
Lillian Nail

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe have previously reported that 1 year of supervised resistance + impact training stopped bone loss and built muscle strength in older breast cancer survivors. The purpose of this study was to determine whether these benefits persisted 1 year after completion of the intervention.

methodsSixty-seven women from the original trial completed baseline and post-intervention body composition and muscle strength tests, and 44 women were available 1 year later for follow-up assessments. Bone mineral density (grams per square centimeter) of the hip and spine, muscle mass (kilograms), and fat mass (kilograms) were measured by dual-energy X-ray absorptiometry and maximal upper and lower body strength were measured by one-repetition maximum tests (kilograms). We compared between group changes across baseline (pre-intervention), 1 (post-intervention), and 2 years (1 year follow up) on study outcomes using repeated-measures analysis of covariance, adjusting for age.

resultsSignificant group by time interactions were found for spine bone mineral density (BMD) (p < 0.01) and lower body muscle strength (p < 0.05), with a trend for upper body muscle strength (p = 0.05). Spine BMD remained stable across intervention and follow-up periods in exercisers compared with continuous losses in controls across 1- and 2-year periods. In contrast, lower body strength increased in exercisers across the intervention, but decreased to near-baseline levels during follow-up compared with no change over either time period in controls.

conclusionsOur data suggest that spine BMD can be preserved in older breast cancer survivors even after formal exercise training stops; however, muscle strength is not similarly maintained and may require continued participation in a supervised exercise program. IMPLICATIONS FOR CANCER SURVIVORS: Exercise programs aimed at improving musculoskeletal health should be considered in the long-term care plan for breast cancer survivors.

Indexed as

Body CompositionBone DensityExerciseMuscle StrengthSurvivorsAgedBreast NeoplasmsFemaleHumansMiddle AgedResistance Training

Identifiers

PMID24317968

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.