Trial reportNutrients2013
Changes in blood pressure and lipid levels in young women consuming a vitamin D-fortified skimmed milk: a randomised controlled trial.
Trial report in Nutrients, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01739907 (Iron-fortified Flavoured Skimmed Milk With or Without Vitamin D in Iron Deficient Women), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Iron-fortified Flavoured Skimmed Milk With or Without Vitamin D in Iron Deficient Women
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Effect of Vitamin D on Blood Pressure and Hypertension in the General Population: An Update Meta-Analysis of Cohort Studies and Randomized Controlled Trials.Preventing chronic disease · 2020Pooled it
- Effect of Vitamin D Supplementation on Blood Pressure: A Systematic Review and Meta-analysis Incorporating Individual Patient Data.JAMA internal medicine · 2015Pooled it
- Serum 25-hydroxyvitamin D response to vitamin D supplementation using different lipid delivery systems in middle-aged and older adults: a randomised controlled trial.The British journal of nutrition · 2023Trial
- Effect of vitamin D supplementation versus placebo on essential hypertension in patients with vitamin D deficiency: a double-blind randomized clinical trial.Journal of clinical hypertension (Greenwich, Conn.) · 2020Trial
- Review
- Fortification of Staple Foods for Household Use with Vitamin D: An Overview of Systematic Reviews.Nutrients · 2023Review
- Sex and Age Differences Modulate Association of Vitamin D with Serum Triglyceride Levels.Journal of personalized medicine · 2022Article
- Extra-Skeletal Effects of Vitamin D.Nutrients · 2019Review
- Vitamin D and Hypertension.Electrolyte & blood pressure : E & BP · 2017Review
- Seasonal variations of vitamin D and its relation to lipid profile in Iranian children and adults.Journal of health, population, and nutrition · 2017Article
- Discrepant association of serum C-3 epimer of 25-hydroxyvitamin D versus non-epimeric 25-hydroxyvitamin D with serum lipid levels.Lipids in health and disease · 2016Article
- Age and sex differences in the relationship between serum 25-hydroxyvitamin D and hypertension in the general Korean population.European journal of clinical nutrition · 2016Article
- Determinants of vitamin D deficiency among undergraduate medical students in Saudi Arabia.European journal of clinical nutrition · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledVitamin D exerts a variety of extra-skeletal functions.
aimto know the effects of the consumption of a vitamin D-fortified skimmed milk on glucose, lipid profile, and blood pressure in young women.
methodsa randomised, placebo-controlled, double-blind parallel-group trial of 16 weeks duration was conducted in young women with low iron stores who consumed a skimmed milk fortified with iron and 200 IU/day (5 μg) of vitamin D (D-fortified group, n = 55), or a placebo without vitamin D (D-placebo group, n = 54). A reference group (n = 56) of iron-sufficient women was also recruited.
resultsbaseline serum 25-hydroxyvitamin D was inversely correlated with total-cholesterol (r = -0.176, p = 0.023) and low density lipoprotein-cholesterol (LDL-chol) (r = -0.176, p = 0.024). During the assay, LDL-cholesterol increased in the D-placebo group (p = 0.005) while it tended to decrease in the D-fortified group (p = 0.07). Neither group displayed changes in total-cholesterol, high density lipoprotein-cholesterol (HDL-chol), triglycerides or glucose levels. Systolic (p = 0.017) and diastolic (p = 0.010) blood pressure decreased during the assay in the D-fortified group without significant differences compared to the D-placebo.
conclusionconsumption of a dairy product fortified with vitamin D reduces systolic and diastolic blood pressure but does not change lipid levels in young women.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.