SynthesisMedicina oral, patologia oral y cirugia bucal2014
Efficacy of platelet-rich plasma applied to post-extraction retained lower third molar alveoli. A systematic review.
Synthesis in Medicina oral, patologia oral y cirugia bucal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 5 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Interventions to minimize periodontal defect distal to second molar after mandibular third molar surgery: an overview of systematic reviews.Oral and maxillofacial surgery · 2025Pooled it
- Performance of blood concentrates in controlling inflammatory signs and symptoms after lower third molar extractions: an overview.Acta cirurgica brasileira · 2025Pooled it
- Do blood concentrates influence inflammatory signs and symptoms after mandibular third molar surgery? A systematic review and network meta-analysis of randomized clinical trials.Clinical oral investigations · 2023Pooled it
- Local interventions for the management of alveolar osteitis (dry socket).The Cochrane database of systematic reviews · 2022Pooled it
- Efficacy of different methods used for dry socket prevention and risk factor analysis: A systematic review.Medicina oral, patologia oral y cirugia bucal · 2017Pooled it
- Effects of the Application of an Oxygen-Enriched Oil-Based Dressing (NovoXJournal of clinical medicine · 2025Article
- PRF and PRP in Dentistry: An Umbrella Review.Journal of clinical medicine · 2025Review
- Blood concentrates for controlling postoperative complications from third molar surgeries: a scoping review.Acta cirurgica brasileira · 2025Article
- The effects of lyophilised platelet-rich plasma in third molar extraction sockets and its surrounding tissues.Journal of Taibah University Medical Sciences · 2022Article
- Angiogenesis and the prevention of alveolar osteitis: a review study.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledDental retentions have a high prevalence among the general population and their removal can involve multiple complications. The use of platelet rich plasma has been proposed in an attempt to avoid these complications, as it contains high growth factors and stimulates diverse biological functions that facilitate the healing of soft and hard tissues.
objectivesTo evaluate the available scientific evidence related to the application of platelet-rich plasma in the post-extraction alveoli of a retained lower third molars. MATERIAL AND
methodsA systematic review of published literature registered in the Medline, EMBASE, Cochrane and NIH databases. The following categories were included: human randomized clinical studies. Key search words were: platelet rich plasma; platelet rich plasma and oral surgery; platelet rich in growth factors and third molar.
resultsOf 101 potentially valid articles, seven were selected, of which four were rejected as they failed to meet quality criteria. Three studies fulfilled all selection and quality criteria: Ogundipe et al.; Rutkowski et al.; Haraji et al. The studies all measured osteoblast activity by means of sintigraphy, and also registered pain, bleeding, inflammation, temperature, numbness as perceived by the patients, radiological bone density and the incidence of alveolar osteitis.
conclusionsScientific evidence for the use of PRP in retained third molar surgery is poor. For this reason randomized clinical trials are needed before recommendations for the clinical application of PRP can be made.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.