Evidence map›Paper›PMID 24316052›Full record

ArticleJournal of biomedical informatics2014

Federated Aggregate Cohort Estimator (FACE): an easy to deploy, vendor neutral, multi-institutional cohort query architecture.

Matthew C Wyatt, R Curtis Hendrickson, Michael Ames, Jessica Bondy, Paul Ranauro, Thomas M English, Keith Bobitt, Arthur Davidson, Thomas K Houston, Peter J Embi and 1 more

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Towards cross-application model-agnostic federated cohort discovery.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  2. Article
  3. Privacy Policy and Technology in Biomedical Data Science.Annual review of biomedical data science · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthew C WyattBiomedical Informatics, Center for Clinical and Translational Science, University of Alabama at Birmingham, Suit 175 Sparks Building, 1720 7th Avenue South, Birmingham, AL 35233, United States. Electronic address: mwyatt@uabmc.edu.
R Curtis HendricksonBiomedical Informatics, Center for Clinical and Translational Science, University of Alabama at Birmingham, Suit 175 Sparks Building, 1720 7th Avenue South, Birmingham, AL 35233, United States.
Michael AmesUniversity of Colorado Cancer Center, 13001 E. 17th Place, Aurora, CO 80045, United States.
Jessica BondyUniversity of Colorado Cancer Center, 13001 E. 17th Place, Aurora, CO 80045, United States.
Paul RanauroResearch Computing Services, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655-0002, United States.
Thomas M EnglishDepartment of Quantitative Health Sciences, University of Massachusetts Medical School, AS8-1063, 368 Plantation Street, Worcester, MA 01605, United States.
Keith BobittBiomedical Informatics, Center for Clinical and Translational Science, University of Alabama at Birmingham, Suit 175 Sparks Building, 1720 7th Avenue South, Birmingham, AL 35233, United States.
Arthur DavidsonDenver Public Health, Denver Health, 605 Bannock Street, Denver, CO 80204, United States.
Thomas K HoustonDepartment of Quantitative Health Sciences, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655-0002, United States.
Peter J EmbiDepartment of Biomedical Informatics, The Ohio State University College of Medicine, 3190 Graves Hall, 333 W. Tenth Avenue, Columbus, OH 43210, United States.
Eta S BernerHealth Informatics Program, Department of Health Services Administration, University of Alabama at Birmingham, 1705 University Blvd #590J, Birmingham, AL 35294-1212, United States.

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Colorado Clinical and Translational Science Institute (UL1)UL1TR000154 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2012 to 2013
$20.4M
University of Massachusetts Center for Clinical and Translational ScienceUL1TR000161 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2015
$11.0M
UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
The Ohio State University Center for Clinical and Translational Science (UL1)UL1TR000090 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$7.9M
NCATS NIH HHS UL1 TR000090NCATS NIH HHS UL1TR000090NCATS NIH HHS UL1 TR000154NCATS NIH HHS UL1TR000154NCATS NIH HHS UL1 TR000161NCATS NIH HHS UL1TR000161NCATS NIH HHS UL1 TR000165NCATS NIH HHS UL1TR000165NCATS NIH HHS UL1 TR001082
6 · The paper itself

Abstract

Cross-institutional data sharing for cohort discovery is critical to enabling future research. While particularly useful in rare diseases, the ability to target enrollment and to determine if an institution has a sufficient number of patients is valuable in all research, particularly in the initiation of projects and collaborations. An optimal technology solution would work with any source database with minimal resource investment for deployment and would meet all necessary security and confidentiality requirements of participating organizations. We describe a platform-neutral reference implementation to meet these requirements: the Federated Aggregate Cohort Estimator (FACE). FACE was developed and implemented through a collaboration of The University of Alabama at Birmingham (UAB), The Ohio State University (OSU), the University of Massachusetts Medical School (UMMS), and the Denver Health and Hospital Authority (DHHA) a clinical affiliate of the Colorado Clinical and Translational Sciences Institute. The reference implementation of FACE federated diverse SQL data sources and an i2b2 instance to estimate combined research subject availability from three institutions. It used easily-deployed virtual machines and addressed privacy and security concerns for data sharing.

Indexed as

Computer SecurityConfidentialityHumansInformation DisseminationInformation Storage and RetrievalMedical InformaticsUser-Computer InterfaceCohort discoveryData sharingFederated queryGrid architecturei2b2TRIAD

Identifiers

PMID24316052
PMCPMC4045656

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.