Evidence map›Paper›PMID 24315715›Full record

ArticleJournal of pediatric and adolescent gynecology2014

Adolescents' and young women's use of a microbicide surrogate product when receiving oral sex.

Beth A Auslander, Marina Catallozzi, Gray Davis, Paul A Succop, Lawrence R Stanberry, Susan L Rosenthal

Abstract read
In one paragraph

Article in Journal of pediatric and adolescent gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beth A AuslanderDepartment of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX. Electronic address: baauslan@utmb.edu.
Marina CatallozziDepartment of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY; Department of Population and Family Health, Columbia University Medical Center-Mailman School of Public Health and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
Gray DavisGray Davis Consulting, Raleigh-Durham, NC.
Paul A SuccopDepartment of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH.
Lawrence R StanberryDepartment of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
Susan L RosenthalDepartment of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY; Department of Psychiatry, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.

Funding

ZOLLINGER-ELLISON SYNDROME AND DUODONAL ULCER DISEASEM01RR000073 · NCRR · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ANDERSON, KARL ELMO · 1985 to 2009
$31.3M
T. vaginalis Recurrence Among HIV+ WomenU19AI061972 · NIAID · LSU HEALTH SCIENCES CENTER · PI TAYLOR, STEPHANIE N · 2004 to 2009
$12.0M
Adolescent and Parental Attitudes About STI Prevention Trial ParticipationR01HD067287 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROSENTHAL, SUSAN L · 2011 to 2015
$2.8M
MICROBICIDES: DEVELOPMENTAL CONTEXT OF ACCEPTABILITYR01HD040151 · NICHD · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ROSENTHAL, SUSAN L · 2000 to 2004
$2.0M
Planning for a Phase 2/2b Microbicide Study: VivaGel for HSV Prevention in WomenR34AI090051 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STANBERRY, LAWRENCE · 2010 to 2010
$206k
NCRR NIH HHS M01 RR000073NIAID NIH HHS R34 AI090051NIAID NIH HHS U19 AI061972NICHD NIH HHS R01 HD040151NICHD NIH HHS R01 HD067287
6 · The paper itself

Abstract

STUDY

objectiveGenital herpes, which can be spread through oral sex, is an important target for microbicides. We examined episode-specific predictors of young women's receptive oral sex and of microbicide surrogate use.

designLongitudinal study.

settingParticipants were recruited to participate in a microbicide acceptability study from adolescent clinics and local colleges and through snowballing.

participantsYoung women (ages 14 to 21 y) who reported sexual contact on at least 1 weekly phone interview (n = 181) were included from the larger sample of 208 young women.

main outcome measuresOn weekly diary phone interviews, participants reported whether or not their last sexual contact included receptive oral sex and whether or not their last sexual contact included use of a microbicide surrogate. RESULTS AND

conclusionsParticipants reported a total of 1042 episodes of sexual contact of which 311 included receptive oral sex and 354 included microbicide surrogate use. Being older, having sex for the first time with a partner, and having given oral sex were associated with having received oral sex during a sexual episode. Being older, being African American, and having discussed the microbicide surrogate with their partner were associated with having used the microbicide surrogate use during a sexual episode. These results indicate that oral sex should be considered in the design of clinical trials. Future studies need to evaluate ways to promote consistent microbicide use in the context of receiving oral sex as well as those factors (eg, taste, pleasure) which may serve as a barrier.

Indexed as

Sexual BehaviorAdministration, TopicalAdolescentAge FactorsAnti-Infective AgentsBlack or African AmericanCommunicationDrug CombinationsFemaleGlycerolHerpes GenitalisHumansLipidsLongitudinal StudiesMalePolyethylene GlycolsAnti-Infective AgentsDrug CombinationsGlycerolLipidslubrinPolyethylene GlycolsReplensVaginal Creams, Foams, and JelliesAdolescentsGenital herpesMicrobicidesOral sexSexually transmitted infections

Identifiers

PMID24315715
PMCPMC4365499

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.