Evidence map›Paper›PMID 24315411›Full record

ReviewBiological psychiatry2014

Diagnosis and management of behavioral variant frontotemporal dementia.

Peter S Pressman, Bruce L Miller

Open access · greenAbstract readReview
In one paragraph

Review in Biological psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 4 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 4 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Premorbid de novo artistic creativity in frontotemporal dementia (FTD) syndromes.Journal of neural transmission (Vienna, Austria : 1996) · 2021
    Pooled it
  4. Pooled it
  5. Article
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  12. Frontal Disorders and Consciousness: A Review.Current neurology and neuroscience reports · 2025
    Review
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  17. Review
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  19. Article
  20. Inappropriate trusting behaviour in dementia.Frontiers in neurology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Peter S PressmanMemory and Aging Center, Department of Neurology, University of California at San Francisco, San Francisco, California. Electronic address: ppressman@memory.ucsf.edu.
Bruce L MillerMemory and Aging Center, Department of Neurology, University of California at San Francisco, San Francisco, California.
University Memory and Aging Center · US

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
PrPSc SPECIFIC INTERACTION WITH NOVEL PrP-Fc FUSION PROTEINSP50AG023501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MILLER, BRUCE L · 2004 to 2018
$27.1M
NIA NIH HHS P01 AG019724NIA NIH HHS P01AG019724NIA NIH HHS P50 AG023501NIA NIH HHS P50AG023501
6 · The paper itself

Abstract

Frontotemporal dementia was documented over a century ago. The last decade, however, has seen substantial changes in our conceptions of this increasingly recognized disorder. Different clinical variants have been delineated, the most common of which is the behavioral variant (bvFTD). Updated diagnostic criteria have been established. New histopathological findings and genetic etiologies have been discovered. Research continues to uncover molecular mechanisms by which abnormal proteins accumulate in degenerating brain tissue. Novel neuroimaging techniques suggest that functional networks are diminished in bvFTD that might be relevant to empathy and social behavior. Despite rapid advances in our understanding of bvFTD, the disease is still under-recognized and commonly misdiagnosed. The result is inappropriate patient care. Recognizing the various presentations of bvFTD and its histological and genetic subtypes might further diagnosis, treatment, and research.

Indexed as

BrainFrontotemporal DementiaHumansBehavioral variant frontotemporal dementiabvFTDfrontotemporal dementiafrontotemporal lobar degenerationFTDPick’s disease

Identifiers

PMID24315411
PMCPMC4194080
OpenAlexW2073906214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.