Evidence map›Paper›PMID 24315364›Full record

ArticleCell metabolism2013

Adipose tissue macrophages: Amicus adipem?

Justin I Odegaard, Kirthana Ganeshan, Ajay Chawla

Abstract readComment
In one paragraph

Article in Cell metabolism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Norepinephrine promotes triglyceride storage in macrophages via beta2-adrenergic receptor activation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  7. The Beige Adipocyte as a Therapy for Metabolic Diseases.International journal of molecular sciences · 2019
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Justin I OdegaardCardiovascular Research Institute, University of California, San Francisco, 94158-9001, USA.
Kirthana Ganeshan
Ajay Chawla

Funding

Innate Immune Mechanisms of ThermogenesisR01DK094641 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, BIAO · 2011 to 2019
$3.5M
Transcriptional Control of Macrophage in AtherogenesisR01HL076746 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAWLA, AJAY · 2004 to 2014
$3.0M
Immune Triggers of Tissue RegenerationDP1AR064158 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAWLA, AJAY · 2012 to 2013
$1.5M
NHLBI NIH HHS R01 HL076746NIAMS NIH HHS DP1 AR064158NIDDK NIH HHS R01 DK094641
6 · The paper itself

Abstract

Chronic overnutrition drives complex adaptations within both professional metabolic and bystander tissues that, despite intense investigation, are still poorly understood. Xu et al. (2013) now describe the unexpected ability of adipose tissue macrophages to buffer lipids released from obese adipocytes in a manner independent of inflammatory macrophage activation.

Indexed as

Adipose TissueAnimalsLipid MetabolismLysosomesMacrophages

Identifiers

PMID24315364
PMCPMC3899686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.