ReviewAmerican journal of ophthalmology2014
Autoimmune retinopathy.
Review in American journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
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Who cites it
66 citing papers in PubMed, 151 citations in OpenAlex.
- Autoimmune retinopathy inAmerican journal of ophthalmology case reports · 2026Article
- Paraneoplastic syndromes and the retina.Current opinion in ophthalmology · 2026Review
- Unilateral pigmentary retinopathy in an Asian population.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- Acquired bipolar cell disorder presenting with photophobia.BMC ophthalmology · 2025Article
- Diagnosis and treatment of autoimmune retinopathy: review of current approaches.International ophthalmology · 2025Review
- Autoimmune encephalitis associated with antibodies against α-enolase sequestrated from degenerating retina in retinitis pigmentosa.BMC ophthalmology · 2025Article
- Anti-retinal Autoantibodies in Hydroxychloroquine Eye Toxicity.ACR open rheumatology · 2025Article
- Article
- Application of Ophthalmic Electrophysiology in Inflammatory Disorders of Retina and Optic Nerve.Journal of clinical medicine · 2024Review
- Hematopoietic stem cell transplantation as rescue therapy for refractory autoimmune retinopathy: a case report.Frontiers in immunology · 2024Article
- Structural and Functional Changes in Non-Paraneoplastic Autoimmune Retinopathy.Diagnostics (Basel, Switzerland) · 2023Article
- Acute bilateral blindness due to diffuse outer retinopathy following clear lens exchange: a case report.BMC ophthalmology · 2023Article
- Serum antiretinal antibodies and cytokine profiling in autoimmune retinopathy and their association with clinical outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Management of autoimmune retinopathy treated with intravitreal dexamethasone implant.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Limited Clinical Value of Anti-Retinal Antibody Titers and Numbers in Autoimmune Retinopathy.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Retinopathy as an initial sign of hereditary immunological diseases: report of six families and challenges in eye clinic.Frontiers in immunology · 2023Article
- Proteomic analysis of autoimmune retinopathy implicates NrCAM as a potential biomarker.Ophthalmology science · 2022Article
- Autoimmune retinopathy: clinical, electrophysiological, and immunological features in nine patients with long-term follow-up.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Autoimmune Retinopathy, Testing, and Its Controversies.Current ophthalmology reports · 2021Article
- Autoantibody profiles and clinical association in Thai patients with autoimmune retinopathy.Scientific reports · 2021Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo provide a detailed review of current clinical guidelines for the diagnosis, work-up and treatment of autoimmune retinopathy and to preview briefly possible future therapies.
designPerspective based on literature review and clinical expertise.
methodsInterpretation of current literature, relying on the authors' clinical experience.
resultsAutoimmune retinopathy is a rare immunologic disease characterized by the presence of circulating antiretinal antibodies along with electroretinographic and visual field abnormalities. An ophthalmic examination can be normal or show minimal findings. The diagnosis of autoimmune retinopathy is made difficult by diagnostic criteria that are both limited and nonstandardized. Currently, the diagnosis is made based on the demonstration of serum antiretinal antibodies and the presence of clinical manifestations (including abnormal electroretinographic findings). The mere presence of these antibodies is not diagnostic. Lack of an accepted gold standard for antiretinal antibodies detection and poor interlaboratory concordance make the diagnosis challenging. There are anecdotal reports of immunosuppressive therapy in autoimmune retinopathy; however, the response to treatment is variable, with more favorable results achieved in paraneoplastic retinopathy, particularly cancer-associated retinopathy, with a combination of chemotherapy and immunosuppression. Whether an earlier attempt to treat nonparaneoplastic autoimmune retinopathy would be more beneficial is unknown. Early treatment attempts are limited by lack of sensitive and specific assays and definitive clinical criteria.
conclusionsLittle is known about the clinical course, prognosis and treatment of autoimmune retinopathy. Additional studies should examine the specificity and pathogenicity of antiretinal antibodies and screen for biomarkers, and they should be conducted concurrently with studies seeking to identify appropriate treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.