ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2014
Commentary on "The influence of lung airways branching structure and diffusion time on measurements and models of short-range 3He gas MR diffusion".
Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Functional imaging of the lungs with gas agents.Journal of magnetic resonance imaging : JMRI · 2016Review
- Noninvasive quantification of alveolar morphometry in elderly never- and ex-smokers.Physiological reports · 2015Article
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Authors and funding
3 authors.
Funding
Abstract
In a recently published paper by Parra-Robles and Wild, the authors challenge the in vivo lung morphometry technique (based on hyperpolarized gas diffusion MRI) developed by our Washington University research group. In this Commentary we demonstrate that the main conclusion of Parra-Robles and Wild, that our MRI-based lung morphometry technique "produces inaccurate estimates of the airway dimensions", does not have any scientific basis and is not in agreement with the considerable body of peer-reviewed scientific reports as well as with Parra-Robles and Wild's own data. On the contrary, our technique has a strong theoretical background, is validated, and provides accurate 3D tomographic information on lung microstructural parameters previously available only from invasive biopsy specimens. This technique has already produced a number of results related to lung morphology and function that were not previously available. In our Commentary we also discuss a number of other incorrect statements in and shortcomings of Parra-Robles and Wild's paper.
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Registered trials
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