ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2014
Middle East respiratory syndrome coronavirus not detected in children hospitalized with acute respiratory illness in Amman, Jordan, March 2010 to September 2012.
Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Dam-Infant Rhesus Macaque Pairs to Dissect Age-Dependent Responses to SARS-CoV-2 Infection.ImmunoHorizons · 2022Article
- Middle East Respiratory Syndrome (MERS) Virus-Pathophysiological Axis and the Current Treatment Strategies.AAPS PharmSciTech · 2021Review
- MERS-CoV: epidemiology, molecular dynamics, therapeutics, and future challenges.Annals of clinical microbiology and antimicrobials · 2021Review
- Review
- Coronavirus infections in children: from SARS and MERS to COVID-19, a narrative review of epidemiological and clinical features.Acta bio-medica : Atenei Parmensis · 2020Review
- Children in Coronaviruses' Wonderland: What Clinicians Need to Know.Mediterranean journal of hematology and infectious diseases · 2020Review
- Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan.BMJ open · 2018Article
- Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia.World journal of clinical pediatrics · 2016Article
- Drivers of MERS-CoV transmission: what do we know?Expert review of respiratory medicine · 2016Review
- MERS coronavirus: diagnostics, epidemiology and transmission.Virology journal · 2015Review
- Human Metapneumovirus Infection in Jordanian Children: Epidemiology and Risk Factors for Severe Disease.The Pediatric infectious disease journal · 2015Article
- Article
- Middle East respiratory syndrome coronavirus (MERS-CoV): what lessons can we learn?The Journal of hospital infection · 2015Review
- Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd.Virus research · 2015Review
- Middle East respiratory syndrome coronavirus in children.Saudi medical journal · 2015Review
- Stillbirth during infection with Middle East respiratory syndrome coronavirus.The Journal of infectious diseases · 2014Article
- Performance and clinical validation of the RealStar MERS-CoV Kit for detection of Middle East respiratory syndrome coronavirus RNA.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2014Article
- Real-time reverse transcription-PCR assay panel for Middle East respiratory syndrome coronavirus.Journal of clinical microbiology · 2014Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
Hospitalized children < 2 years of age in Amman, Jordan, admitted for fever and/or respiratory symptoms, were tested for Middle East respiratory syndrome coronavirus (MERS-CoV): MERS-CoV by real-time RT-PCR (rRT-PCR). This was a prospective year-round viral surveillance study in children <2 years of age admitted with acute respiratory symptoms and/or fever from March 2010 to September 2012 and enrolled from a government-run hospital, Al-Bashir in Amman, Jordan. Clinical and demographic data, including antibiotic use, were collected. Combined nasal/throat swabs were collected, aliquoted, and frozen at -80°C. Specimen aliquots were shipped to Vanderbilt University and the Centers for Disease Control and Prevention (CDC), and tested by rRT-PCR for MERS-CoV. Of the 2433 subjects enrolled from 16 March 2010 to 10 September 2012, 2427 subjects had viral testing and clinical data. Of 1898 specimens prospectively tested for other viruses between 16 March 2010 and 18 March 2012, 474 samples did not have other common respiratory viruses detected. These samples were tested at CDC for MERS-CoV and all were negative by rRT-PCR for MERS-CoV. Of the remaining 531 samples, collected from 19 March 2012 to 10 September 2012 and tested at Vanderbilt, none were positive for MERS-CoV. Our negative findings from a large sample of young Jordanian children hospitalized with fever and/or respiratory symptoms suggest that MERS-CoV was not widely circulating in Amman, Jordan, during the 30-month period of prospective, active surveillance occurring before and after the first documented MERS-CoV outbreak in the Middle East region.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.