Evidence map›Paper›PMID 24312744›Full record

ArticleBiomedical optics express2013

Variational analysis of the mouse and rat eye optical parameters.

Gurinder Bawa, Tatiana V Tkatchenko, Ivan Avrutsky, Andrei V Tkatchenko

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Safety Profile of Slit-Lamp-Delivered Retinal Laser Photobiomodulation.Translational vision science & technology · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Species Differences in the Geometry of the Anterior Segment Differentially Affect Anterior Chamber Cell Scoring Systems in Laboratory Animals.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gurinder BawaDepartment of Electrical and Computer Engineering, Wayne State University, Detroit, MI 48201 USA.
Tatiana V Tkatchenko
Ivan Avrutsky
Andrei V Tkatchenko
Wayne State University · US

Funding

Feasibility of a mouse model of myopiaR21EY018902 · NEI · WAYNE STATE UNIVERSITY · PI TKATCHENKO, ANDREI V. · 2009 to 2010
$405k
NEI NIH HHS R21 EY018902
6 · The paper itself

Abstract

Rodent models are increasingly used to study refractive eye development and development of refractive errors; however, there is still some uncertainty regarding the accuracy of the optical models of the rat and mouse eye primarily due to high variability in reported ocular parameters. In this work, we have systematically evaluated the contribution of various ocular parameters, such as radii of curvature of ocular surfaces, thicknesses of ocular components, and refractive indices of ocular refractive media, using variational analysis and a computational model of the rodent eye. Variational analysis revealed that not all variation in ocular parameters has critical impact on the refractive status of the eye. Variation in the depth of the vitreous chamber, thickness of the lens, radius of the anterior surface of the cornea, radius of the anterior surface of the lens, as well as refractive indices for the lens and vitreous, appears to have the largest impact on the refractive error. The radii of the posterior surfaces of the cornea and lens have much smaller contributions to the refractive state. These data provide the framework for further refinement of the optical models of the rat and mouse eye and suggest that extra efforts should be directed towards increasing the linear resolution of the rodent eye biometry and obtaining more accurate data for the refractive indices of the lens and vitreous.

Indexed as

(000.1430) Biology and medicine(080.0080) Geometric optics(080.1753) Computation methods(170.0170) Medical optics and biotechnology(170.3660) Light propagation in tissues(170.4460) Ophthalmic optics and devices(170.4470) Ophthalmology(330.0330) Vision, color, and visual optics(330.7326) Visual optics, modeling

Identifiers

PMID24312744
PMCPMC3829552
OpenAlexW1964303344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.