ArticleGut and liver2013
Intra-abdominal pressure in the early phase of severe acute pancreatitis: canary in a coal mine? Results from a rigorous validation protocol.
Article in Gut and liver, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Intra-abdominal Hypertension Is a Strong Predictor of Mortality and Poor Clinical Outcome in Severe Acute Pancreatitis.Digestive diseases and sciences · 2025Pooled it
- Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis.Critical care (London, England) · 2022Trial
- Article
- Intra-abdominal hypertension and abdominal compartment syndrome in acute pancreatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Review
- Abdominal Compartment Syndrome in Acute Pancreatitis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Intra-Abdominal Hypertension: A Systemic Complication of Severe Acute Pancreatitis.Medicina (Kaunas, Lithuania) · 2022Review
- Computed tomography features predictive of intra-abdominal hypertension in acute necrotizing pancreatitis: A prospective study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- Potential Prognostic Markers of Acute Kidney Injury in the Early Phase of Acute Pancreatitis.International journal of molecular sciences · 2019Review
- Intra-abdominal pressure: Time ripe to revise management guidelines of acute pancreatitis?World journal of gastrointestinal pathophysiology · 2016Article
- Surgery for Acute Pancreatitis.The Indian journal of surgery · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsIntra-abdominal hypertension (IAH) is being increasingly reported in patients with severe acute pancreatitis (SAP) with worsened outcomes. The present study was undertaken to evaluate intra-abdominal pressure (IAP) as a marker of severity in the entire spectrum of acute pancreatitis and to ascertain the relationship between IAP and development of complications in patients with SAP.
methodsIAP was measured via the transvesical route by measurements performed at admission, once after controlling pain and then every 4 hours. Data were collected on the length of the hospital stay, the development of systemic inflammatory response syndrome (SIRS), multiorgan failure, the extent of necrosis, the presence of infection, pleural effusion, and mortality.
resultsIn total, 40 patients were enrolled and followed up for 30 days. The development of IAH was exclusively associated with SAP with an APACHE II score ≥8 and/or persistent SIRS, identifying all patients who were going to develop abdominal compartment syndrome (ACS). The presence of ACS was associated with a significantly increased extent of pancreatic necrosis, multiple organ failure, and mortality. The mean admission IAP value did not differ significantly from the value obtained after pain control or the maximum IAP measured in the first 5 days.
conclusionsIAH is reliable marker of severe disease, and patients who manifest organ failure, persistent SIRS, or an Acute Physiology and Chronic health Evaluation II score ≥8 should be offered IAP surveillance. Severe pancreatitis is not a homogenous entity.
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