ArticlePloS one2013
Down-regulation of OsSPX1 causes high sensitivity to cold and oxidative stresses in rice seedlings.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Candidate genes identification for internode length in rice via genome-wide association studies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- The SPX protein family in plants: from phosphate sensors to multifunctional signaling hubs.Stress biology · 2026Review
- Genome-wide identification, expression analysis, and response to abiotic stress of the phosphate transporter gene family in cucumber (Cucumis sativus L.).BMC plant biology · 2025Article
- Nuclear lamina component KAKU4 regulates chromatin states and transcriptional regulation in the Arabidopsis genome.BMC biology · 2024Article
- KAKU4 regulates leaf senescence through modulation of H3K27me3 deposition in the Arabidopsis genome.BMC plant biology · 2024Article
- Genome-wide identification and expression analysis of phosphate-sensing SPX proteins in oats.Frontiers in genetics · 2024Article
- Abiotic Stress in Rice: Visiting the Physiological Response and Its Tolerance Mechanisms.Plants (Basel, Switzerland) · 2023Review
- Identification of candidate genes that regulate the trade-off between seedling cold tolerance and fruit quality in melon (Horticulture research · 2023Article
- Genome-Wide Identification and Analysis of OsSPXs Revealed Its Genetic Influence on Cold Tolerance of Dongxiang Wild Rice (DXWR).International journal of molecular sciences · 2023Article
- Convergence and Divergence: Signal Perception and Transduction Mechanisms of Cold Stress inPlants (Basel, Switzerland) · 2021Review
- A CCR4-associated factor 1, OsCAF1B, confers tolerance of low-temperature stress to rice seedlings.Plant molecular biology · 2021Article
- Integrated RNA-Seq Analysis and Meta-QTLs Mapping Provide Insights into Cold Stress Response in Rice Seedling Roots.International journal of molecular sciences · 2020Article
- Cytochrome P450 metabolism mediates low-temperature resistance in pinewood nematode.FEBS open bio · 2020Article
- Article
- The Maize Sulfite Reductase Is Involved in Cold and Oxidative Stress Responses.Frontiers in plant science · 2018Article
- Response of microRNAs to cold treatment in the young spikes of common wheat.BMC genomics · 2017Article
- Trait and Marker Associations inFrontiers in plant science · 2017Article
- Genome-Wide Identification and Analysis of Genes, Conserved betweenFrontiers in plant science · 2017Article
- Down-regulation of OsSPX1 caused semi-male sterility, resulting in reduction of grain yield in rice.Plant biotechnology journal · 2016Article
- CaPUB1, a Hot Pepper U-box E3 Ubiquitin Ligase, Confers Enhanced Cold Stress Tolerance and Decreased Drought Stress Tolerance in Transgenic Rice (Oryza sativa L.).Molecules and cells · 2016Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rice SPX domain gene, OsSPX1, plays an important role in the phosphate (Pi) signaling network. Our previous work showed that constitutive overexpression of OsSPX1 in tobacco and Arabidopsis plants improved cold tolerance while also decreasing total leaf Pi. In the present study, we generated rice antisense and sense transgenic lines of OsSPX1 and found that down-regulation of OsSPX1 caused high sensitivity to cold and oxidative stresses in rice seedlings. Compared to wild-type and OsSPX1-sense transgenic lines, more hydrogen peroxide accumulated in seedling leaves of OsSPX1-antisense transgenic lines for controls, cold and methyl viologen (MV) treatments. Glutathione as a ROS scavenger could protect the antisense transgenic lines from cold and MV stress. Rice whole genome GeneChip analysis showed that some oxidative-stress marker genes (e.g. glutathione S-transferase and P450s) and Pi-signaling pathway related genes (e.g. OsPHO2) were significantly down-regulated by the antisense of OsSPX1. The microarray results were validated by real-time RT-PCR. Our study indicated that OsSPX1 may be involved in cross-talks between oxidative stress, cold stress and phosphate homeostasis in rice seedling leaves.
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