ArticlePloS one2013
Comparison of diagnostic value of conventional ultrasonography and shear wave elastography in the prediction of thyroid lesions malignancy.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Comparison of diagnostic yield of core-needle and fine-needle aspiration biopsies of thyroid lesions: Systematic review and meta-analysis.European radiology · 2017Pooled it
- Pooled it
- Shear wave elastography in the diagnostics of parathyroid adenomas-new application of the method.Endocrine · 2018Trial
- Article
- Assessing the Recovery of Muscle Fatigue Using Shear Wave Elastography.Sports medicine - open · 2026Article
- Evaluating the clinical impact of integrating superb microvascular imaging and shear wave elastography into TI-RADS.Journal of ultrasound · 2025Article
- Elastography of the thyroid nodule, cut-off points between benign and malignant lesions for strain, 2D shear wave real time and point shear wave: a correlation with pathology, ACR TIRADS and Alpha Score.Frontiers in endocrinology · 2023Article
- Evaluation of thyroid nodules by shear wave elastography: a review of current knowledge.Journal of endocrinological investigation · 2021Review
- Sonographic Features Differentiating Follicular Thyroid Cancer from Follicular Adenoma-A Meta-Analysis.Cancers · 2021Article
- Interobserver Agreement and Plane-Dependent Intraobserver Variability of Shear Wave Sonoelastography in the Differential Diagnosis of Ectopic Thymus Tissue.Journal of clinical medicine · 2021Article
- The Role of Shear Wave Elastography in the Discrimination Between Malignant and Benign Thyroid Nodules.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020Article
- S-Detect Software vs. EU-TIRADS Classification: A Dual-Center Validation of Diagnostic Performance in Differentiation of Thyroid Nodules.Journal of clinical medicine · 2020Article
- Application of shear wave elastography and B-mode ultrasound in patellar tendinopathy after extracorporeal shockwave therapy.Journal of medical ultrasonics (2001) · 2020Article
- Difference-Frequency Ultrasound Imaging With Non-Linear Contrast.IEEE transactions on medical imaging · 2020Article
- Elastography for the diagnosis of high-suspicion thyroid nodules based on the 2015 American Thyroid Association guidelines: a multicenter study.BMC endocrine disorders · 2020Article
- Correlations between Molecular Landscape and Sonographic Image of Different Variants of Papillary Thyroid Carcinoma.Journal of clinical medicine · 2019Review
- Prospective analysis of inter-observer and intra-observer variability in multi ultrasound descriptor assessment of thyroid nodules.Journal of ultrasonography · 2019Article
- Histopathological Verification of the Diagnostic Performance of the EU-TIRADS Classification of Thyroid Nodules-Results of a Multicenter Study Performed in a Previously Iodine-Deficient Region.Journal of clinical medicine · 2019Article
- Reappraisal of shear wave elastography as a diagnostic tool for identifying thyroid carcinoma.Endocrine connections · 2019Article
- Mechanical properties and morphologic features of intrinsic foot muscles and plantar fascia in individuals with hallux valgus.Acta orthopaedica et traumatologica turcica · 2019Article
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Authors and funding
8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionThyroid nodular disease (TND) is a very common disorder. However, since the rate of malignancy is reported to be 3-10%, only a minority of patients require aggressive surgical treatment. As a result, there is a need for diagnostic tools which would allow for a reliable differentiation between benign and malignant nodules. Although a number of conventional ultrasonographic (US) features are proved to be markers of malignancy, Shear Wave Elastography (SWE) is considered to be an improvement of conventional US. The aim of this study was to compare conventional US markers and SWE diagnostic values in the differentiation of benign and malignant thyroid nodules. MATERIALS AND
methodsAll patients referred for thyroidectomy, irrespective of the indications, underwent a US thyroid examination prospectively. Patients with TND were included into the study. Results of the US and SWE examinations were compared with post-surgical histopathology.
resultsOne hundred and twenty two patients with 393 thyroid nodules were included into the study. Twenty two patients were diagnosed with cancer. SWE turned out to be a predictor of malignancy superior to any other conventional US markers (OR=54.5 using qualitative scales and 40.8 using quantitative data on maximal stiffness with a threshold of 50 kPa).
conclusionsAlthough most conventional US markers of malignancy prove to be significant, none of them are characterized by both high sensitivity and specificity. SWE seems to be an important step forward, allowing for a more reliable distinction of benign and malignant thyroid nodules. Our study, assessing SWE properties on the highest number of thyroid lesions at the time of publication, confirms the high diagnostic value of this technique. It also indicates that a quantitative evaluation of thyroid lesions is not superior to simpler qualitative methods.
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