ArticlePloS one2013
Information transmission in a neuron-astrocyte coupled model.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Bifurcation analysis and diverse firing activities of a modified excitable neuron model.Cognitive neurodynamics · 2019Article
- Computational Models for Calcium-Mediated Astrocyte Functions.Frontiers in computational neuroscience · 2018Review
- Lévy noise improves the electrical activity in a neuron under electromagnetic radiation.PloS one · 2017Article
- Dynamic transition of neuronal firing induced by abnormal astrocytic glutamate oscillation.Scientific reports · 2016Article
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Authors and funding
3 authors.
Funding
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Abstract
A coupled model containing two neurons and one astrocyte is constructed by integrating Hodgkin-Huxley neuronal model and Li-Rinzel calcium model. Based on this hybrid model, information transmission between neurons is studied numerically. Our results show that when the successive spikes are produced in neuron 1 (N1), the bursting-like spikes (BLSs) occur in two neurons simultaneously during the spikes being transferred to neuron 2 (N2). The existence of the astrocyte and a higher expression level of mGluRs facilitate the occurrence of BLSs, but the rate of occurrence is not sensitive to the parameters. Furthermore, time delay τ occurs during the information transmission, and τ is almost independent of the effect of the astrocyte. Additionally, we found that low coupling strength may result in the distortion of the information, and this distortion is also proven to be almost independent of the astrocyte.
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