Evidence map›Paper›PMID 24312158›Full record

ReviewTheranostics2013

Positron emission tomography imaging of atherosclerosis.

Hakan Orbay, Hao Hong, Yin Zhang, Weibo Cai

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Diverse applications and development of aptamer detection technology.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Review
  2. Nanomaterial-based contrast agents.Nature reviews. Methods primers · 2023
    Article
  3. Review
  4. Enzyme-activated probes in optical imaging: a focus on atherosclerosis.Dalton transactions (Cambridge, England : 2003) · 2021
    Review
  5. Review
  6. Article
  7. Calcium-binding nanoparticles for vascular disease.Regenerative engineering and translational medicine · 2019
    Article
  8. Diagnostic imaging in the management of patients with metabolic syndrome.Translational research : the journal of laboratory and clinical medicine · 2018
    Review
  9. Integrin signaling in atherosclerosis.Cellular and molecular life sciences : CMLS · 2017
    Review
  10. Systems Biology and Noninvasive Imaging of Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2016
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Photoacoustic Microscopy in Tissue Engineering.Materials today (Kidlington, England) · 2013
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hakan Orbay1. Department of Radiology, University of Wisconsin - Madison, WI, USA;
Hao Hong
Yin Zhang
Weibo Cai
University of Wisconsin–Madison · US

Funding

Novel Combination Therapy for Prostate CancerR01CA169365 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CAI, WEIBO · 2013 to 2015
$903k
NCI NIH HHS 1R01CA169365NCI NIH HHS R01 CA169365
6 · The paper itself

Abstract

Atherosclerosis-related cardiovascular events are the leading causes of death in the industrialized world. Atherosclerosis develops insidiously and the initial manifestation is usually sudden cardiac death, stroke, or myocardial infarction. Molecular imaging is a valuable tool to identify the disease at an early stage before fatal manifestations occur. Among the various molecular imaging techniques, this review mainly focuses on positron emission tomography (PET) imaging of atherosclerosis. The targets and pathways that have been investigated to date for PET imaging of atherosclerosis include: glycolysis, cell membrane metabolism (phosphatidylcholine synthesis), integrin αvβ3, low density lipoprotein (LDL) receptors (LDLr), natriuretic peptide clearance receptors (NPCRs), fatty acid synthesis, vascular cell adhesion molecule-1 (VCAM-1), macrophages, platelets, etc. Many PET tracers have been investigated clinically for imaging of atherosclerosis. Early diagnosis of atherosclerotic lesions by PET imaging can help to prevent the premature death caused by atherosclerosis, and smooth translation of promising PET tracers into the clinic is critical to the benefit of patients.

Indexed as

AtherosclerosisEarly DiagnosisHumansPositron-Emission Tomographyatherosclerosiscardiovascular diseases.molecular imagingPositron emission tomography (PET)vulnerable plaques

Identifiers

PMID24312158
PMCPMC3841339
OpenAlexW2028376650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.