ArticleFrontiers in human neuroscience2013
On ERPs detection in disorders of consciousness rehabilitation.
Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.
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Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Care pathways for individuals with post-anoxic disorder of consciousness (CaPIADoC): an inter-society Consensus Conference.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- EEG-based Brain-Computer Interfaces for people with Disorders of Consciousness: Features and applications. A systematic review.Frontiers in human neuroscience · 2022Pooled it
- Managing disorders of consciousness: the role of electroencephalography.Journal of neurology · 2021Pooled it
- Techniques of cognitive rehabilitation in patients with disorders of consciousness: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018Pooled it
- Research progress on occupational therapy for disorders of consciousness in the context of neurorehabilitation: visual analysis based on CiteSpace.Frontiers in neurologyPooled it
- Impact of Gentle Touch Stimulation Combined with Advanced Sensory Stimulation in Patients in a Minimally Conscious State: A Quasi-Randomized Clinical Trial.Life (Basel, Switzerland) · 2025Article
- Analysis of the microstates of prolonged disorders of consciousness.Frontiers in neurology · 2025Article
- The effect of neural pre-stimulus oscillations on post-stimulus auditory ERPs in disorders of consciousness.Frontiers in neuroscience · 2025Article
- The Prognostic Role of Candidate Serum Biomarkers in the Post-Acute and Chronic Phases of Disorder of Consciousness: A Preliminary Study.Brain sciences · 2024Article
- A study on EEG differences between active counting and focused breathing tasks for more sensitive detection of consciousness.Frontiers in neuroscience · 2024Article
- Neurophysiological and Psychometric Outcomes in Minimal Consciousness State after Advanced Audio-Video Emotional Stimulation: A Retrospective Study.Brain sciences · 2023Article
- Electroencephalogram-Based Brain Connectivity Analysis in Prolonged Disorders of Consciousness.Neural plasticity · 2023Article
- A Potential Prognosis Indicator Based on P300 Brain-Computer Interface for Patients with Disorder of Consciousness.Brain sciences · 2022Article
- Development of an Italian version of the functional communication measures and preliminary observations in patients with severe acquired brain injury and emerging from a prolonged disorder of consciousness.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Assessing residual motor function in patients with disorders of consciousness by brain network properties of task-state EEG.Cognitive neurodynamics · 2022Article
- Brain-Computer Interfaces for Awareness Detection, Auxiliary Diagnosis, Prognosis, and Rehabilitation in Patients with Disorders of Consciousness.Seminars in neurology · 2022Review
- A simple intervention for disorders of consciousness- is there a light at the end of the tunnel?Frontiers in neurology · 2022Article
- Frontal and parietal lobes play crucial roles in understanding the disorder of consciousness: A perspective from electroencephalogram studies.Frontiers in neuroscience · 2022Review
- Spontaneous eye blinking as a diagnostic marker in prolonged disorders of consciousness.Scientific reports · 2021Article
- Virtually spatialized sounds enhance auditory processing in healthy participants and patients with a disorder of consciousness.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disorders of Consciousness (DOC) like Vegetative State (VS), and Minimally Conscious State (MCS) are clinical conditions characterized by the absence or intermittent behavioral responsiveness. A neurophysiological monitoring of parameters like Event-Related Potentials (ERPs) could be a first step to follow-up the clinical evolution of these patients during their rehabilitation phase. Eleven patients diagnosed as VS (n = 8) and MCS (n = 3) by means of the JFK Coma Recovery Scale Revised (CRS-R) underwent scalp EEG recordings during the delivery of a 3-stimuli auditory oddball paradigm, which included standard, deviant tones and the subject own name (SON) presented as a novel stimulus, administered under passive and active conditions. Four patients who showed a change in their clinical status as detected by means of the CRS-R (i.e., moved from VS to MCS), were subjected to a second EEG recording session. All patients, but one (anoxic etiology), showed ERP components such as mismatch negativity (MMN) and novelty P300 (nP3) under passive condition. When patients were asked to count the novel stimuli (active condition), the nP3 component displayed a significant increase in amplitude (p = 0.009) and a wider topographical distribution with respect to the passive listening, only in MCS. In 2 out of the 4 patients who underwent a second recording session consistently with their transition from VS to MCS, the nP3 component elicited by passive listening of SON stimuli revealed a significant amplitude increment (p < 0.05). Most relevant, the amplitude of the nP3 component in the active condition, acquired in each patient and in all recording sessions, displayed a significant positive correlation with the total scores (p = 0.004) and with the auditory sub-scores (p < 0.00001) of the CRS-R administered before each EEG recording. As such, the present findings corroborate the value of ERPs monitoring in DOC patients to investigate residual unconscious and conscious cognitive function.
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