Evidence map›Paper›PMID 24312012›Full record

ArticleFrontiers in cellular neuroscience2013

From Drosophila development to adult: clues to Notch function in long-term memory.

Jiabin Zhang, Jerry C P Yin, Cedric S Wesley

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jiabin ZhangNeuroscience Training Program, University of Wisconsin-Madison Madison, WI, USA ; Department of Genetics and Medical Genetics, University of Wisconsin-Madison Madison, WI, USA.
Jerry C P Yin
Cedric S Wesley
University of Wisconsin–Madison · US

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 1985 to 2015
$25.2M
Sleep and Memory Formation in DrosophilaR01NS063245 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI YIN, JERRY C · 2009 to 2013
$1.6M
Variation in maternal and zygotic control of embryogenesis events in DrosophilaR21HD062928 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI WESLEY, CEDRIC S · 2010 to 2011
$399k
NICHD NIH HHS P30 HD003352NICHD NIH HHS R21 HD062928NINDS NIH HHS R01 NS063245
6 · The paper itself

Abstract

Notch is a cell surface receptor that is well known to mediate inter-cellular communication during animal development. Data in the field indicate that it is also involved in the formation of long-term memory (LTM) in the fully developed adults and in memory loss upon neurodegeneration. Our studies in the model organism Drosophila reveal that a non-canonical Notch-protein kinase C activity that plays critical roles in embryonic development also regulates cyclic-AMP response element binding protein during LTM formation in adults. Here we present a perspective on how the various known features of Notch function relate to LTM formation and how they might interface with elements of Wingless/Wnt signaling in this process.

Indexed as

CREBF-actinIκBLTMneurodegenerationnotchPKCWnt

Identifiers

PMID24312012
PMCPMC3836050
OpenAlexW2114540005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.