Evidence map›Paper›PMID 24311847›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2013

Anti-bacterial activities and phytochemical screening of extracts of different parts of Thalictrum rhynchocarpum.

Philip Wafula Mayeku, Ahmed Hassanali, Bernard Turyagenda Kiremire, Josiah Ochieng Odalo, Christian Hertweck

Open access · diamondAbstract read
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. A Systematic Review of Medicinal Plants of Kenya used in the Management of Bacterial Infections.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Philip Wafula MayekuDepartment of Chemistry, Makerere University, P. O. Box 7062, Kampala, Uganda.
Ahmed Hassanali
Bernard Turyagenda Kiremire
Josiah Ochieng Odalo
Christian Hertweck
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEMakerere University · UGTechnical University of Mombasa · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parts of the plant Thalictrum rhyncocarpum are used in herbal medicine in Kenya to treat various infections. The aim of this study was to evaluate in-vitro anti-bacteria activities and phytochemical profiles of solvent extracts of the leaves, stem bark and root of Thalictrum rhyncocarpum against Bacillus subtilis-6633, Staphylococcus aures-SG 511, Escherichia coli SG 458, Pseudomonus aeruginosa-K799/61 and Mycobacterium vaccae-10670. Anti-bacterial activity tests were carried out using disc diffusion assay and tube dilution technique, and phytochemical screening was carried out through Thin Layer Chromatography. The crude extracts showed antibacterial effects on M. vaccae, P. aeruginosa and B. subtilis. M. vaccae was most sensitive, particularly to the methanol root extract. Phytochemical screening of the extracts suggested the presence of glycosides and alkaloids in the stem bark and root extracts, and flavonoids and triterpenes in the leaf extracts. The study showed interesting levels of activities of solvent extracts of different parts of T. rhyncocarpum against some of the bacteria tested (M. vaccae, P. aeruginosa and B. subtilis). The results provide some scientific rationale for the traditional use of the plant in Kenya to treat different microbial infections.

Indexed as

AlkaloidsAnti-Bacterial AgentsBacteriaFlavonoidsGlycosidesMicrobial Sensitivity TestsPlant ExtractsPlant StructuresThalictrumTriterpenesAlkaloidsAnti-Bacterial AgentsFlavonoidsGlycosidesPlant ExtractsTriterpenesAnti-microbial activitiesEthno-medicinal plantPhytochemical profileThalictrum rhyncocarpum

Identifiers

PMID24311847
PMCPMC3847427
OpenAlexW2162447900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.