GuidelineZeitschrift fur Rheumatologie2014
[Recommendations of the German Society for Rheumatology on the perioperative approach under therapy with DMARDs and biologicals in inflammatory rheumatic diseases].
Guideline in Zeitschrift fur Rheumatologie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- [Long version on the S3 guidelines for axial spondyloarthritis including Bechterew's disease and early forms, Update 2019 : Evidence-based guidelines of the German Society for Rheumatology (DGRh) and participating medical scientific specialist societies and other organizations].Zeitschrift fur Rheumatologie · 2019Guideline
- [Recommendations for use of abatacept in patients with rheumatoid arthritis].Zeitschrift fur Rheumatologie · 2014Guideline
- [Septic musculoskeletal complications under immunomodulating treatment].Zeitschrift fur Rheumatologie · 2025Review
- Study on the Mechanism of the Combination of Methotrexate and Leflunomide in the Treatment of Rheumatoid Arthritis Based on Network Pharmacology, Molecular Docking, andCombinatorial chemistry & high throughput screening · 2025Article
- Orthognathic surgery in patients with systemic diseases.Oral and maxillofacial surgery · 2023Article
- [Multimodal rheumatological complex treatment : A current inventory].Zeitschrift fur Rheumatologie · 2022Review
- [Perioperative management of treatment of patients with inflammatory rheumatic diseases : Updated recommendations of the German Society of Rheumatology].Zeitschrift fur Rheumatologie · 2022Article
- Microangiopathy in Inflammatory Diseases-Strategies in Surgery of the Lower Extremity.Life (Basel, Switzerland) · 2022Article
- [Therapeutic options in juvenile idiopathic arthritis : Surgical and conservative orthopedic rheumatological treatment].Zeitschrift fur Rheumatologie · 2021Article
- [Perioperative management in the treatment of trauma for rheumatics under immunosuppression].Der Unfallchirurg · 2020Review
- [Management of early rheumatoid arthritis : Interdisciplinary guideline].Zeitschrift fur Rheumatologie · 2020Review
- [Immunosuppressive treatment and bone healing].Der Unfallchirurg · 2019Review
- Current Therapeutic Options in the Treatment of Rheumatoid Arthritis.Journal of clinical medicine · 2019Review
- [The knee joint in rheumatoid arthritis-current orthopaedic surgical treatment options].Zeitschrift fur Rheumatologie · 2018Review
- [Complications in orthopedic rheumatology-characteristics of operative procedures].Der Orthopade · 2018Review
- [Surgical management of ankylosing spondylitis (Bechterew's disease)].Zeitschrift fur Rheumatologie · 2017Review
- [Perioperative management of immunosuppressive treatment in patients undergoing joint surgery].Zeitschrift fur Rheumatologie · 2017Review
- Article
- [Psoriatic arthritis : Overview of drug therapy options and administration characteristics].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017Review
- [Psoriatic arthritis : Overview of drug therapy options and administration characteristics].Zeitschrift fur Rheumatologie · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe perioperative administration of antirheumatic medication can lead to an increased risk of infection and to a malfunction in wound healing up to a manifest infection; however, the termination of antirheumatic therapy can result in a flare up of the disease. Both situations can endanger the success of the operation, particularly in arthroplasty.
methodThe recommendations have been developed and approved by the Pharmacotherapy Commission of the German Society for Rheumatology following a systematic literature search (as of 30 April 2013) and a consensus process.
resultsAs very little data with sufficiently high evidence are available, the present recommendations should be considered as having an advisory quality and an individual risk assessment should always be carried out. Classical disease-modifying antirheumatic drugs (DMARD), such as methotrexate can be continued in normal cases but whether this is also true for leflunomide is still undecided. For biologicals a break of two half-life periods before the operation is recommended. The therapy can be continued after wound healing has been completed and when there are no signs of infection.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.