Evidence for including lutein and zeaxanthin in oral supplements for age-related macular degeneration.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

1. Systematic review of the appropriateness of eye care delivery in eye care practice.BMC health services research · 2019
   Pooled it
2. Lutein nanodisks protect human retinal pigment epithelial cells from UV light-induced damage.Frontiers in nanotechnology · 2022
   Article
3. Challenges in Age-Related Macular Degeneration: From Risk Factors to Novel Diagnostics and Prevention Strategies.Frontiers in medicine · 2022
   Review
4. Polypeptide - decorated nanoliposomes as novel delivery systems for lutein.RSC advances · 2018
   Article
5. Combined influence of poor health behaviours on the prevalence and 15-year incidence of age-related macular degeneration.Scientific reports · 2017
   Article
6. The Pharmacological Effects of Lutein and Zeaxanthin on Visual Disorders and Cognition Diseases.Molecules (Basel, Switzerland) · 2017
   Review
7. Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review.Oxidative medicine and cellular longevity · 2017
   Review
8. Joint Associations of Diet, Lifestyle, and Genes with Age-Related Macular Degeneration.Ophthalmology · 2015
   Article
9. Marine Carotenoids against Oxidative Stress: Effects on Human Health.Marine drugs · 2015
   Review
10. Carotenoids: potential allies of cardiovascular health?Food & nutrition research · 2015
    Article
11. Age-related Eye Disease Study 2: perspectives, recommendations, and unanswered questions.Current opinion in ophthalmology · 2014
    Review

Corrections and comments

• Commented on by
  Experimental design issue for assessment of carotenoids lutein and zeaxanthin in age-related eye disease study 2 formulation for age-related macular degeneration.2014
• Commented on by
  Making sense of the evidence from the age-related eye disease study 2 randomized clinical trial.2014
• Commented on by
  Making sense of the evidence from the age-related eye disease study 2 randomized clinical trial-reply.2014
• Comment on
  Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3.2014

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as