ArticleBiomicrofluidics2013
Entropic depletion of DNA in triangular nanochannels.
Article in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Article
- Dynamic simulations show repeated narrowing maximizes DNA linearization in elastomeric nanochannels.Biomicrofluidics · 2016Article
- Modeling the relaxation of internal DNA segments during genome mapping in nanochannels.Biomicrofluidics · 2016Article
- Kirkwood diffusivity of long semiflexible chains in nanochannel confinement.Macromolecules · 2015Article
- Hydrodynamics of DNA confined in nanoslits and nanochannels.The European physical journal. Special topics · 2014Article
- Stretching of DNA confined in nanochannels with charged walls.Biomicrofluidics · 2014Article
- Interplay between chain stiffness and excluded volume of semiflexible polymers confined in nanochannels.The Journal of chemical physics · 2014Article
- Simulations of DNA stretching by flow field in microchannels with complex geometry.Biomicrofluidics · 2014Article
- Modeling the relaxation time of DNA confined in a nanochannel.Biomicrofluidics · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Using Monte Carlo simulations of a touching-bead model of double-stranded DNA, we show that DNA extension is enhanced in isosceles triangular nanochannels (relative to a circular nanochannel of the same effective size) due to entropic depletion in the channel corners. The extent of the enhanced extension depends non-monotonically on both the accessible area of the nanochannel and the apex angle of the triangle. We also develop a metric to quantify the extent of entropic depletion, thereby collapsing the extension data for circular, square, and various triangular nanochannels onto a single master curve for channel sizes in the transition between the Odijk and de Gennes regimes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.