ArticleBrain stimulation
FMRI of deep brain stimulation at the rat ventral posteromedial thalamus.
Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Systematic review of rodent studies of deep brain stimulation for the treatment of neurological, developmental and neuropsychiatric disorders.Translational psychiatry · 2024Pooled it
- Neuromodulation in Small Animal fMRI.Journal of magnetic resonance imaging : JMRI · 2025Review
- Elucidating hemodynamics and neuro-glio-vascular signaling using rodent fMRI.Trends in neurosciences · 2025Review
- Activation mapping in multi-center retrospective rat sensory-evoked functional MRI datasets using a unified pipeline.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Topiramate suppresses peri-infarct spreading depolarization and improves outcomes in a rat model of photothrombotic stroke.iScience · 2024Article
- Novel Composite Gold-Aluminum Electrode with Application to Neural Recording and Stimulation in Ultrahigh Field Magnetic Resonance Imaging Scanners.Annals of biomedical engineering · 2021Article
- Spontaneous BOLD waves - A novel hemodynamic activity in Sprague-Dawley rat brain detected by functional magnetic resonance imaging.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- Average firing rate rather than temporal pattern determines metabolic cost of activity in thalamocortical relay neurons.Scientific reports · 2019Article
- Mapping stress networks using functional magnetic resonance imaging in awake animals.Neurobiology of stress · 2018Review
- MB-SWIFT functional MRI during deep brain stimulation in rats.NeuroImage · 2017Article
- Coordination of Brain-Wide Activity Dynamics by Dopaminergic Neurons.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Article
- Functional circuit mapping of striatal output nuclei using simultaneous deep brain stimulation and fMRI.NeuroImage · 2017Article
- Functional Magnetic Resonance Imaging of Electrical and Optogenetic Deep Brain Stimulation at the Rat Nucleus Accumbens.Scientific reports · 2016Article
- Hippocampal deep brain stimulation reduces glucose utilization in the healthy rat brain.Molecular imaging and biology · 2015Article
- A programmable high-voltage compliance neural stimulator for deep brain stimulation in vivo.Sensors (Basel, Switzerland) · 2015Article
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Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundFunctional magnetic resonance imaging (fMRI) of deep brain stimulation (DBS) has potentials to reveal neuroanatomical connectivity of a specific brain region in vivo.
objectiveThis study aimed to demonstrate frequency and amplitude tunings of the thalamocortical tract using DBS fMRI at the rat ventral posteromedial thalamus.
methodsBlood oxygenation level dependent (BOLD) fMRI data were acquired in a total of twelve rats at a high-field 11.7 T MRI scanner with modulation of nine stimulus frequencies (1-40 Hz) and seven stimulus amplitudes (0.2-3.6 mA).
resultsBOLD response in the barrel cortex peaked at 25 Hz. The response increased with stimulus amplitude and reached a plateau at 1 mA. Cortical spreading depolarization (CSD) was observed occasionally after DBS that carries >10% BOLD waves spanning the entire ipsilateral cortex.
conclusionfMRI is sensitive to the frequency effect of DBS and has potential to investigate the function of a particular neuroanatomical pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.