Evidence map›Paper›PMID 24308516›Full record

ArticleEpidemiology and infection2014

Norovirus genotypes implicated in two oyster-related illness outbreaks in Ireland.

P Rajko-Nenow, S Keaveney, J Flannery, A McINTYRE, W Doré

Abstract read
In one paragraph

Article in Epidemiology and infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Norovirus Infection in Harbor Porpoises.Emerging infectious diseases · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P Rajko-NenowMarine Institute,Rinville, Oranmore, Co. Galway,Ireland.
S KeaveneyMarine Institute,Rinville, Oranmore, Co. Galway,Ireland.
J FlanneryMarine Institute,Rinville, Oranmore, Co. Galway,Ireland.
A McINTYREMarine Institute,Rinville, Oranmore, Co. Galway,Ireland.
W DoréMarine Institute,Rinville, Oranmore, Co. Galway,Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated norovirus (NoV) concentrations and genotypes in oyster and faecal samples associated with two separate oyster-related outbreaks of gastroenteritis in Ireland. Quantitative analysis was performed using real-time quantitative reverse transcription polymerase chain reaction and phylogenetic analysis was conducted to establish the NoV genotypes present. For both outbreaks, the NoV concentration in oysters was >1000 genome copies/g digestive tissue and multiple genotypes were identified. In faecal samples, GII.13 was the only genotype detected for outbreak 1, whereas multiple genotypes were detected in outbreak 2 following the application of cloning procedures. While various genotypes were identified in oyster samples, not all were successful in causing infection in consumers. In outbreak 2 NoV GII.1 was identified in all four faecal samples analysed and NoV GII concentrations in faecal samples were >108 copies/g. This study demonstrates that a range of NoV genotypes can be present in highly contaminated oysters responsible for gastroenteritis outbreaks.

Indexed as

Disease OutbreaksAnimalsCaliciviridae InfectionsFecesGastroenteritisGenotypeHumansIrelandMolecular EpidemiologyNorovirusOstreidaeReal-Time Polymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionRNA, ViralViral LoadRNA, Viral

Identifiers

PMID24308516
PMCPMC9151252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.