Evidence map›Paper›PMID 24308495›Full record

ArticleAmerican journal of respiratory and critical care medicine2014

Persistent latent tuberculosis reactivation risk in United States immigrants.

Nicholas D Walter, John Painter, Matthew Parker, Phillip Lowenthal, Jennifer Flood, Yunxin Fu, Redentor Asis, Randall Reves, Tuberculosis Epidemiologic Studies Consortium

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Trends in tuberculosis clinicians' adoption of short-course regimens for latent tuberculosis infection.Journal of clinical tuberculosis and other mycobacterial diseases · 2023
    Article
  5. Article
  6. Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions.International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Article
  9. TB risk by time since U.S. entry among non-U.S.-born residents of Washington State, USA.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2021
    Article
  10. Article
  11. Cost-effectiveness of the latent tuberculosis screening program for migrants in Stockholm Region.The European journal of health economics : HEPAC : health economics in prevention and care · 2021
    Article
  12. Review
  13. Article
  14. Finding and Closing the Gaps in the Tuberculosis Elimination Campaign.Annals of the American Thoracic Society · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nicholas D Walter1 Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Aurora, Colorado.
John Painter
Matthew Parker
Phillip Lowenthal
Jennifer Flood
Yunxin Fu
Redentor Asis
Randall Reves
Tuberculosis Epidemiologic Studies Consortium

Funding

Colorado Career Development Program in the Genetics and Genomics of Lung DiseasesK12HL090147 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI GERACI, MARK W · 2007 to 2012
$2.0M
NHLBI NIH HHS K-12 5K12HL090147-04NHLBI NIH HHS K12 HL090147
6 · The paper itself

Abstract

rationaleCurrent guidelines limit latent tuberculosis infection (LTBI) evaluation to persons in the United States less than or equal to 5 years based on the assumption that high TB rates among recent entrants are attributable to high LTBI reactivation risk, which declines over time. We hypothesized that high postarrival TB rates may instead be caused by imported active TB.

objectivesEstimate reactivation and imported TB in an immigrant cohort.

methodsWe linked preimmigration records from a cohort of California-bound Filipino immigrants during 2001-2010 with subsequent TB reports. TB was likely LTBI reactivation if the immigrant had no evidence of active TB at preimmigration examination, likely imported if preimmigration radiograph was abnormal and TB was reported less than or equal to 6 months after arrival, and likely reactivation of inactive TB if radiograph was abnormal but TB was reported more than 6 months after arrival. MEASUREMENTS AND MAIN

resultsAmong 123,114 immigrants, 793 TB cases were reported. Within 1 year of preimmigration examination, 85% of TB was imported; 6 and 9% were reactivation of LTBI and inactive TB, respectively. Conversely, during Years 2-9 after U.S. entry, 76 and 24% were reactivation of LTBI and inactive TB, respectively. The rate of LTBI reactivation (32 per 100,000) did not decline during Years 1-9.

conclusionsHigh postarrival TB rates were caused by detection of imported TB through active postarrival surveillance. Among immigrants without active TB at baseline, reported TB did not decline over 9 years, indicating sustained high risk of LTBI reactivation. Revised guidelines should support LTBI screening and treatment more than 5 years after U.S. arrival.

Indexed as

AdultAgedAge FactorsCaliforniaEmigrants and ImmigrantsFemaleHumansLatent TuberculosisMaleMiddle AgedPhilippinesRecurrenceTuberculosis, PulmonaryYoung Adult

Identifiers

PMID24308495
PMCPMC3919127

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.